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Special Issue: Analysis of Biological Samples for Chemical Warfare Agents
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JANUARY/FEBRUARY 2008
Editorial, John R. Barr
An Overview of Biological Markers of Exposure to Chemical Warfare Agents,
Robin M. Black
Analysis of Urinary Metabolites of Sulfur Mustard in Two Individuals after Accidental Exposure,
John R. Barr, Carrie L. Pierce, J. Richard Smith, Benedict R. Capacio, Adrian R. Woolfitt, Maria I. Solano, Joe V. Wooten, Sharon W. Lemire, Jerry D. Thomas, Doris H. Ash, and David L. Ashley
Analysis for Plasma Protein Biomarkers Following an Accidental Human Exposure to Sulfur Mustard,
J. Richard Smith, Benedict R. Capacio, William D. Korte, Adrian R. Woolfitt, and John R. Barr
Retrospective Detection of Sulfur Mustard Exposure by Mass Spectrometric Analysis of Adducts to Albumin and Hemoglobin: An In Vivo Study,
D. Noort, A. Fidder, C.E.A.M. Degenhardt-Langelaan, and A.G. Hulst
Improvements in the Methodology of Monitoring Sulfur Mustard Exposure by Gas Chromatography–Mass Spectrometry Analysis of Cleaved and Derivatized Blood Protein Adducts,
Richard J. Lawrence, J. Richard Smith, Brian L. Boyd, and Benedict R. Capacio
Gas Chromatographic–Mass Spectrometric Analysis of Sulfur Mustard-Plasma Protein Adducts: Validation and Use in a Rat Inhalation Model,
Benedict R. Capacio, J. Richard Smith, Richard J. Lawrence, Brian L. Boyd, Alicia M. Witriol, Michele L. Conti, Jennifer L. Collins, and Alfred M. Sciuto
Multianalyte Quantification of Five Sesqui- and Ethyl Ether Oxy-Mustard Metabolites in Human Urine by Liquid Chromatography–Atmospheric Pressure Chemical Ionization Tandem Mass Spectrometry,
Doris H. Ash, Sharon W. Lemire, Sara C. McGrath, Lisa G. McWilliams, and John R. Barr
Development of a Liquid Chromatography–Multiple Reaction Monitoring Procedure for Concurrent Verification of Exposure to Different Forms of Mustard Agents,
Thong-Hiang Yeo, Mer-Lin Ho, and Weng-Keong Loke
Gas Chromatography–Tandem Mass Spectrometry Analysis of Red Blood Cells from Göttingen Minipig® following Whole-Body Vapor Exposure to VX,
C.E. Byers, J.M. McGuire, S.W. Hulet, D.C. Burnett, B.I. Gaviola, E.M. Jakubowski, and S.A. Thomson
A Rapid and Sensitive Technique for Assessing Exposure to VX via GC–MS–MS Analysis,
Jeffrey M. McGuire, Christopher E. Byers, Stanley W. Hulet, Edward M. Jakubowski, and Sandra A. Thomson
Quantification of Nerve Agent VX-Butyrylcholinesterase Adduct Biomarker from an Accidental Exposure,
Maria I. Solano, Jerry Thomas, James T. Taylor, Jeffrey M. McGuire, Edward. M. Jakubowski, Sandra A. Thomson, Vincent L. Maggio, Kerry E. Holland, J. Richard Smith, Benedict Capacio, Adrian R. Woolfitt, David L. Ashley, and John R. Barr
Determination of VX-G Analogue in Red Blood Cells via Gas Chromatography–Tandem Mass Spectrometry Following an Accidental Exposure to VX,
Jeffrey M. McGuire, James T. Taylor, Christopher E. Byers, Edward M. Jakubowski, and Sandra A. Thomson
Quantification of Sarin and Cyclosarin Metabolites Isopropyl Methylphosphonic Acid and Cyclohexyl Methylphosphonic Acid in Minipig Plasma Using Isotope-Dilution and Liquid Chromatography–Time of Flight Mass Spectrometry,
R.A. Evans, E.M. Jakubowski, W.T. Muse, K. Matson, S.W. Hulet, R.J. Mioduszewski, S.A. Thomson, A.L. Totura, J.A. Renner, and C.L. Crouse
A Gas Chromatographic–Mass Spectrometric Approach to Examining Stereoselective Interaction of Human Serum Proteins with Soman,
David T. Yeung, J. Richard Smith, Richard E. Sweeney, David E. Lenz, and Douglas M. Cerasoli
Validation and Application of a Gas Chromatography–Mass Spectrometry Method for Determining Soman Concentration in Rat Plasma Following Low-Level Vapor Exposure,
Julie A. Renner, Paul A. Dabisch, Ronald A. Evans, Jeffrey M. McGuire, Allison L. Totura, Edward M. Jakubowski, and Sandra A. Thomson
3-Chlorotyrosine and 3,5-Dichlorotyrosine as Biomarkers of Respiratory Tract Exposure to Chlorine Gas,
Mark A. Sochaski, Annie M. Jarabek, John Murphy, and Melvin E. Andersen
A Rapid, Cost-Effective Method for Analyzing Organophosphorus Pesticide Metabolites in Human Urine for Counter-Terrorism Response,
Gayanga Weerasekera, Kimberly D. Smith, Larry L. Needham, and Dana B. Barr
Modifications to the Organophosphorus Nerve Agent-Butyrylcholinesterase Adduct Refluoridation Method for Retrospective Analysis of Nerve Agent Exposures,
Kerry E. Holland, Maria I. Solano, Rudolph C. Johnson, Vincent L. Maggio, and John R. Barr
Verification of Exposure to Cholinesterases Inhibitors: Generic Detection of Schedule 1 Nerve Agent Adducts to Human Butyrylcholinesterase,
M.J. van der Schans, A. Fidder, D. van Oeveren, A.G. Hulst, and D. Noort
Special Issue: Society of Forensic Toxicologists, Inc.
Guest Editor: Sarah Kerrigan
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OCTOBER
2007
423 SOFT President’s Letter
424 Prevalence and Disposition of Drugs of Abuse and Opioid Treatment Drugs in Oral Fluid, Edward J. Cone, Joe Clarke, and Lolita Tsanaclis
434 Rapid Quantification of Urinary Oxycodone and Oxymorphone Using Fast Gas Chromatography–Mass Spectrometry, Scott G. McKinley, J. Jacob Snyder, Eric Welsh, Charles M. Kazarian, Matthew H. Jamerson, and Kevin L. Klette
442 Achieving Proposed Federal Concentrations using Reduced Specimen Volume for the Extraction of Amphetamines from Oral Fluid, Christine Moore, Cynthia Coulter, and Katherine Crompton
447 Stable Isotopes as Valid Components for Identification of Drugs in Biological Specimens, Buddha D. Paul, Justin M. Holler, Timothy P. Lyons, and Marilyn R. Past
453 Quantitative Analysis of Naltrexone and 6β-Naltrexol in Human, Rat, and Rabbit Plasma by Liquid Chromatography–Electrospray Ionization Tandem Mass Spectrometry with Application to the Pharmacokinetics of Depotrex® in Rabbits, Matthew H. Slawson, Meng Chen, David E. Moody, Sandra D. Comer, Elie S. Nuwayser, Wenfang B. Fang, and Rodger L. Foltz
462 Cocaine and Metabolites Urinary Excretion after Controlled Smoked Administration, Marilyn A. Huestis, W. David Darwin, Eric Shimomura, Shairose A. Lalani, Daniel V. Trinidad, Amanda J. Jenkins, Edward J. Cone, Aaron J. Jacobs, Michael L. Smith, and Buddha D. Paul
469 Vitreous Fluid Quantification of Opiates, Cocaine, and Benzoylecgonine: Comparison of Calibration Curves in Both Blood and Vitreous Matrices with Corresponding Concentrations in Blood, Heather M. Antonides, Elizabeth R. Kiely, and Laureen J. Marinetti
477 Simultaneous GC–EI-MS Determination of D9-Tetrahydrocannabinol, 11-Hydroxy-D9-Tetrahydrocannabinol, and 11-nor-9-Carboxy-D9-Tetrahydrocannabinol in Human Urine Following Tandem Enzyme–Alkaline Hydrolysis, Tsadik T. Abraham, Ross H. Lowe, Stephane O. Pirnay, William D. Darwin, and Marilyn A. Huestis
486 Urine pH: the Effects of Time and Temperature after Collection, Janine D. Cook, Kathy A. Strauss, Yale H. Caplan, Charles P. LoDico, and Donna M. Bush
497 Liquid Chromatography–Tandem Mass Spectrometry Method for the Simultaneous Analysis of Multiple Hallucinogens, Chlorpheniramine, Ketamine, Ritalinic Acid, and Metabolites in Urine, Maria del Mar Ramirez Fernandez, Marleen Laloup, Michelle Wood, Gert De Boeck, Manuel Lopez-Rivadulla, Pierre Wallemacq, and Nele Samyn
505 LC–(TOF) MS Analysis of Benzodiazepines in Urine from Alleged Victims of Drug-Facilitated Sexual Assault, Mahmoud A. ElSohly, Waseem Gul, Timothy P. Murphy, Bharathi Avula, and Ikhlas A. Khan
515 Direct-Injection Mass Spectrometric Method for the Rapid Identification of Fentanyl and Norfentanyl in Postmortem Urine of Six Drug-Overdose Cases, Cody J. Peer, Diaa M. Shakleya, Islam R. Younis, James C. Kraner, and Patrick S. Callery
522 CASE REPORT: Loss of Ethanol from Vitreous Humor in Drowning Deaths, Peter P. Singer, Graham R. Jones, Russell Lewis, and Robert Johnson
526 CASE REPORT: The Tissue Distribution of Fluoride in a Fatal Case of Self-Poisoning, María A. Martínez, Salomé Ballesteros, Francisco J. Piga, Carolina Sánchez de la Torre, and Carlos Cubero
534 CASE REPORT: A Fatality from Sevoflurane Abuse, Barry Levine, Dawn Cox, Rebecca A. Jufer Phipps, Ling Li, Aaron Jacobs, and David Fowler
537 CASE REPORT: Distribution of Phencyclidine into Vitreous Humor, Dawn Cox, Rebecca A. Jufer Phipps, Barry Levine, Aaron Jacobs, and David Fowler
540 CASE REPORT: Assessing Free and Total Morphine following Heroin Overdose when Complicated by the Presence of Toxic Amitriptyline Levels, Joseph Avella, Michael Katz, and Michael Lehrer
Special Issue: Society of Forensic
Toxicologists, Inc.
Guest Editor: Marc A. LeBeau
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October 2006
SOFT
President’s Letter
External
Contamination of Hair with Cocaine: Evaluation of External Cocaine
Contamination and Development of Performance Testing Materials,
Peter Stout, Jeri Ropero-Miller, Michael Baylor, and John Mitchell
Major
and Minor Metabolites of Cocaine in Human Plasma following Controlled
Subcutaneous Cocaine Administration,
Erin A Kolbrich, Allan J. Barnes, David A. Gorelick, Susan J.
Boyd, Edward J. Cone, and Marilyn A. Huestis
Cyanide
and Thiocyanate in Human Saliva by Gas Chromatography–Mass
Spectrometry,
Buddha Paul and Michael Smith
Determination
of Propoxyphene in Oral Fluid,
Sumandeep Rana, Christine Moore, Michael Vincent, Cynthia Coulter,
Alpana Agrawal, and James Soares
The
Determination of Morphine in the Larvae of Calliphora stygia using
Flow Injection Analysis and HPLC with Chemiluminescence Detection,
Joshua A. Gunn, Cara Shelley, Simon W. Lewis, Tes Toop, and Melanie
Archer
LC–MS-(TOF)
Analysis Method for Benzodiazepines in Urine Samples from Alleged
Drug-Facilitated Sexual Assault Victims,
Mahmoud A. ElSohly, Waseem Gul, Kareem M. ElSohly, Bharathi Avula,
and Ikhlas A. Khan
Applications
of Ion Mobility Spectrometry (IMS) to the Analysis of gamma-Hydroxybutyrate
and gamma-Hydroxyvalerate in Toxicological Matrices,
Jennifer Mercer, Diaa Shakleya, and Suzanne Bell
Distribution
of Methylenedioxymethamphetamine (MDMA) and Methylenedioxyamphetamine
(MDA) in Postmortem and Antemortem Specimens,
Ray H. Liu, Hsiu-Chuan Liu, and Dong-Liang Lin
Occupational
Exposure to Methamphetamine in Workers Preparing Training Aids
for Drug Detection Dogs,
P.R. Stout, C.K. Horn, K.L. Klette, and J. Given
Rapid
Analysis of Benzoylecgonine in Urine By Fast Gas Chromatography–
Mass Spectrometry,
Robert W. Romberg, Matthew H. Jamerson, and Kevin L. Klette
Validation
of a Headspace GC Method for the Analysis of a Pyrolytic Product
of Methamphetamine in Urine,
Diaa M. Shakleya, James C. Kraner, David J. Clay, Patrick S. Callery,
and Suzanne Bell
Selection
and Optimization of Hydrolysis Conditions for the Quantification
of Urinary Metabolites of MDMA,
Stephane O. Pirnay, Tsadik T. Abraham, Ross H. Lowe, and Marilyn
A. Huestis
Incomplete
Recovery of Prescription Opioids in Urine using Enzymatic Hydrolysis
of Glucuronide Metabolites,
Ping Wang, Judith A. Stone, Katherine H. Chen, Susan F. Gross,
Christine Haller, and Alan H.B. Wu
A
First Look at Duloxetine (Cymbalta®) in a Postmortem Laboratory,
D. Anderson, S. Reed, J. Lintemoor, S. Kegler, S. DeQuintana,
M. Sandberg, and J. Muto
Performance
Evaluation of Thermal Desorption System (TDS) for Detection of
Basic Drugs in Forensic Samples by GC–MS,
Joseph Crifasi, Michael Bruder, Christopher Long, and Kimberly
Janssen
Liquid
Chromatography–Tandem Mass Spectrometry (LC–ESI-MS–MS)
for the Determination of Colchicine in Postmortem Body Fluids.
Case Report of Two Fatalities and Review of the Literature,
Marjorie Chèze, Marc Deveaux, and Gilbert Pépin
Topiramate-Positive
Death-Investigation and Impaired-Driving Cases in Washington State,
Ann Marie Gordon and Barry K. Logan
Fentanyl-Related
Deaths in Ontario, Canada: Toxicological Findings and Circumstances
of Death in 112 Cases (2002–2004),
Teri Martin, Karen Woodall, and Barry McLellan
TECHNICAL
NOTE: Caffeine Content of Decaffeinated Coffee,
Rachel R. McCusker, Brian Fuehrlein, Bruce A. Goldberger, Mark
S. Gold, and Edward J. Cone
TECHNICAL
NOTE: Recovery of Drugs of Abuse from the Immunalysis Quantisal™
Oral Fluid Collection Device,
Oscar Quintela, Dennis J. Crouch, and David M. Andrenyak
TECHNICAL
NOTE: Validation of an ELISA Method for Screening Methadone in
Postmortem Blood,
Matthew Juhascik, Steven Habbel, William Barron, and George Behonick
SHORT
COMMUNICATION: Multi-Element Screening by ICP-MS of Two Specimens
of Napoleon’s Hair,
Pascal Kintz, Morgane Ginet, and Vincent Cirimele
CASE
REPORT: Investigation of a Fatality Due to Diesel Fuel No. 2 Ingestion,
María Martínez and Salomé Ballesteros
CASE
REPORT: Distribution of Ether in Two Postmortem Cases,
Dawn Cox, Rebecca DeRienz, Rebecca A. Jufer Phipps, Barry Levine,
Aaron Jacobs, and David Fowler
CASE
REPORT: A Motor Vehicle Aaccident Fatality Involving the Inhalation
of 1,1-Difluoroethane (DFE, “Dust Off”),
Timothy Hahn, Joseph Avella, and Michael Lehrer
LETTER
TO THE EDITOR: Phencyclidine Detection in Nails,
Amanda J. Jenkins and David A. Engelhart
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Special Issue: Society of Forensic Toxicologists,
Inc.
Guest Editor: Jeri D. Ropero-Miller
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October
2005
Letter
from the President of SOFT
Pharmacogenomics
as Molecular Autopsy for Forensic Toxicology: Genotyping Cytochrome
P450 3A4*1B and 3A5*3 for 25 Fentanyl Cases
Ming Jin, Susan B. Gock, Paul J. Jannetto, Jeffrey M. Jentzen,
and Steven H. Wong
Investigation
of an LC–MS–MS (Qtrap®) Method for the Rapid Screening
and Identification of Drugs in Postmortem Toxicology Whole Blood
Samples,
George L. Herrin, H. Horton McCurdy, and William H. Wall
Passive
Cannabis Smoke Exposure and Oral Fluid Testing. II. Two Studies
of Extreme Cannabis Smoke Exposure in a Motor Vehicle,
R. Sam Niedbala, Keith W. Kardos, Dean F. Fritch, Kenneth P. Kunsman,
Kristen A. Blum, Gregory A. Newland, Joe Waga, Lisa Kurtz, Matth
Bronsgeest, and Edward J. Cone
Validation
of a Liquid Chromatography–Tandem Mass Spectrometry Method
for the Simultaneous Determination of 26 Benzodiazepines and Metabolites,
Zolpidem and Zopiclone, in Blood, Urine, and Hair,
Marleen Laloup, Maria del Mar Ramirez Fernandez, Gert De Boeck,
Michelle Wood, Viviane Maes, and Nele Samyn
Urine
pH, Container Composition, and Exposure Time Influence Adsorptive
Loss of 11-nor-Δ9-Tetrahydrocannabinol-9-Carboxylic Acid,
Matthew H. Jamerson, Joseph J. McCue, and Kevin L. Klette
Usefulness
of Roadside Urine Drug Screening in Drivers Suspected of Driving
Under the Influence of Drugs,
Elke Raes and Alain G. Verstraete
The
Identification of Mivacurium and Metabolites in Biological Samples,
Madeline A. Montgomery, Marc A. LeBeau, Mark L. Miller, and Rebecca
A. Jufer
Investigation
of Fatalities Due to Acute Gasoline Poisoning,
María A. Martínez and Salomé Ballesteros
Quantitative
and Isomeric Determination of Amphetamine and Methamphetamine
from Urine using a Nonprotic Elution Solvent and R(–)-a-Methoxy-a-Trifluoromethylphenylacetic
Acid Chloride Derivatization,
Justin M. Holler, Shawn P. Vorce, Thomas Z. Bosy, and Aaron Jacobs
Spectrophotometric
Detection of Iodide and Chromic (III) in Urine after Oxidation
to Iodine and Chromate (VI),
Buddha D. Paul and Aaron Jacobs
Rapid
Quantification of Urinary 11-nor-Δ9-Tetrahydrocannabinol-9-Carboxylic
Acid using Fast Gas Chromatography–Mass Spectrometry,
Matthew H. Jamerson, Robert M. Welton, Cynthia L. Morris-Kukoski,
and Kevin L. Klette
Rapid
Simultaneous Determination of Amphetamine, Methamphetamine, 3,4-Methylenedioxyamphetamine,
3,4-Methylenedioxymethamphetamine, and 3,4-Methylenedioxyethylamphetamine
in Urine by Fast Gas Chromatography– Mass Spectrometry,
Kevin L. Klette, Matthew H. Jamerson, Cynthia L. Morris-Kukoski,
Aaron R. Kettle, and J. Jacob Snyder
Evaluation
of the DRI® Oxycodone Immunoassay for the Detection of Oxycodone
in Urine,
Ronald C. Backer, Joseph R. Monforte, and Alphonse Poklis
Comparison
of Cozart® Microplate ELISA and GC–MS Detection of Methadone
and Metabolites in Human Hair,
Gail Cooper, Lisa Wilson, Claire Reid, Dene Baldwin, Chris Hand,
and Vina Spiehler
Quantitation
of R-(–)- and S-(+)-Amphetamine in Hair and Blood by Gas
Chromatography–Mass Spectrometry: An Application to Compliance
Monitoring in Adult-Attention Deficit Hyperactivity Disorder Treatment,
Ingrid Nystrom, Tomas Trygg, Per Woxler, Johan Ahlner, and Robert
Kronstrand
Usefulness
of Salivary trans-3'-Hydroxycotinine Concentration and trans-3'-Hydroxycotinine/Cotinine
Ratio as Biomarkers of Cigarette Smoke in Pregnant Women,
Insook Kim, Abraham Wtsadik, Robin E. Choo, Hendree E. Jones,
and Marilyn A. Huestis
Multiple
Aspects of Hair Analysis for Opiates: Methodology, Clinical and
Workplace Populations, and Codeine and Poppy Seed Ingestion,
Virginia Hill, Thomas Cairns, Chen-Chih Cheng, and Michael Schaffer
TECHNICAL
NOTE: Direct Analysis of Opiates in Urine by Liquid Chromatography–Tandem
Mass Spectrometry,
Leslie E. Edinboro, Ronald C. Backer, and Alphonse Poklis
TECHNICAL
NOTE: A Rapid HPLC Procedure for Analysis of Analgesic Pharmaceutical
Mixtures for Quality Assurance and Drug Diversion Testing,
Carl E. Wolf and Alphonse Poklis
TECHNICAL
NOTE: Methylation of 3,4-Methylenedioxymethamphetamine in Formalin-Fixed
Human Liver Tissue,
Diaa M. Shakleya, James C. Kraner, James A. Kaplan, and Patrick
S. Callery
TECHNICAL
NOTE: Performance Characteristics of 7-Aminoflunitrazepam Specific
Enzyme-Linked Immunosorbent Assays,
Dong-Liang Lin, Rea-Ming Yin, Cheng-Hsing Chen, Ya-Lei Chen, and
Ray H. Liu
TECHNICAL
NOTE: Detection of Cannabis Use in Drivers with the Drugwipe Device
and by GC–MS after Intercept Device Collection,
Pascal Kintz, Werner Bernhard, Marion Villain, Martina Gasser,
Beat Aebi, and Vincent Cirimele
TECHNICAL
NOTE: Sample Liquid Chromatographic Method for the Rapid and Simultaneous
Determination of Propoxur and its Major Metabolite Isopropoxy
Phenol in Rat Blood and Urine Using Solid-Phase Extraction,
Ramagiri Suma, R.K. Sarin, P.K. Saiprakash, and Sistla Ramakrishna
CASE
REPORT: Percutaneous Absorption and Distribution of Methanol in
a Homicide,
Joseph Avella, Edward Briglia, Gwendolyn Harleman, and Michael
Lehrer
CASE
REPORT: Over-the-Counter Cold Medications—Postmortem Findings
in Infants and the Relationship to Cause of Death,
Laureen Marinetti, Lee Lehman, Brian Casto, Kent Harshberger,
Piotr Kubiczek, and James Davis
CASE
REPORT: Apparent Suicidal Carbon Monoxide Poisonings with Concomitant
Prescription Drug Overdoses, Avneesh Gupta, Melissa A. Pasquale-Styles,
Bradford R. Hepler, Daniel S. Isenschmid, and Carl J. Schmidt
CASE
REPORT: Tissue Distribution of Loperamide and N-Desmethylloperamide
Following a Fatal Overdose,
Jason Sklerov, Barry Levine, Karla A. Moore, Carol Allan, and
David Fowler
CASE
REPORT: Fatal Seizures Due to Potential Herb-Drug Interactions
with Ginkgo Biloba,
Thomas Kupiec and Vishnu Raj
CASE
REPORT: Determination of l-Methamphetamine: A Case History,
John F. Wyman and John T. Cody
CASE
REPORT: Elevated Postmortem Ethanol Concentrations in an Insulin-Dependent
Diabetic,
Ines B. Collison
LETTER
TO THE EDITOR: Detection of Smoked Cocaine Marker (Anhydroecgonine
Methylester) in Nails,
C. Ragoucy-Sengler and P. Kintz
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Special Issue: 2004 SOFT–TIAFT
Meeting Papers
Guest Editor: Marc LeBeau
JULY/AUGUST 2005
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Ethyl Sulfate: A Metabolite of Ethanol in Humans and a Potential
Biomarker of Acute Alcohol Intake,
A. Helander and O. Beck
Papain:
A Novel Urine Adulterant,
D.L. Burrows, A. Nicolaides, P.J. Rice, M. Dufforc, D.A. Johnson,
and K.E. Ferslew
MDMA
and MDA Concentrations in Antemortem and Postmortem Specimens
in Fatalities Following Hospital Admission,
S.P. Elliott
GC–MS
Quantitation of Codeine, Morphine, 6-Acetylmorphine, Hydrocodone,
Hydromorphone, Oxycodone, and Oxymorphone in Blood,
R. Meatherall
Determination
of Furosemide in Whole Blood Using SPE and GC–EI-MS,
C. Margalho, D. de Boer, E. Gallardo, M. Barroso, and D.N. Vieira
Evaluation
of Ketamine Abuse Using Hair Analysis: Concentration Trends in
a Singapore Population,
H.S. Leong, N.L. Tan, C.P. Lui, and T.K. Lee
Hair
Analysis: The Requirement for Effective Wash Procedures and Effects
of Drug Concentration and Hair Porosity in Contamination and Decontamination,
M. Schaffer, V. Hill, and T. Cairns
Assessment
of Driving Capability Through the Use of Clinical and Psychomotor
Tests in Relation to Blood Cannabinoids Levels Following Oral
Administration of 20 mg Dronabinol or Cannabis Decoction Made
with 20 or 60 mg Δ9-THC,
A. Ménétrey, M. Augsburger, B. Favrat, M.A. Pin,
L.E. Rothuizen, M. Appenzeller, T. Buclin, P. Mangin, and C. Giroud
Amphetamine
Binding to Synthetic Melanin and Scatchard Analysis of Binding
Data,
L. Gautam, K.S. Scott, and M.D. Cole
Opiate
Concentrations in Hair from Subjects in a Controlled Heroin-Maintenance
Program and from Opiate-Associated Fatalities,
F. Musshoff, K. Lachenmeier, H. Wollersen, D. Lichtermann, and
B. Madea
The
Identification of a Chlorinated MDMA,
V. Maresova, J. Hampl, Z. Chundela, F. Zrcek, M. Polasek, and
J. Chadt
TECHNICAL
NOTE: Comparison of the Sensitivity and Specificity of Six Immunoassays
for the Detection of Amphetamines in Urine,
A.G. Verstraete and F. Vander Heyden
TECHNICAL
NOTE: Comparative Alcohol Concentrations in Blood and Vitreous
Fluid With Illustrative Case Studies,
D. Honey, C. Caylor, R. Luthi, and S. Kerrigan
TECHNICAL
NOTE: Gas Chromatography–High-Resolution Mass Spectrometric
Method for Determination of Methamphetamine and Its Major Metabolite
Amphetamine in Human Hair,
J.Y. Kim, S.I. Suh, M.K. In, and B.C. Chung
TECHNICAL
NOTE: Urinary Excretion Rates of Ketamine and Norketaine Following
Therapeutic Ketamine Administration: Method and Detection Window
Consideration,
P. Adamowicz and M. Kala
TECHNICAL
NOTE: Determination of Strychnine in Human Blood using Solid-Phase
Extraction and GC–EI-MS,
M. Barroso, E. Gallardo, C. Margalho, E. Marques, D.N. Vieira,
and M. López-Rivadulla
TECHNICAL
NOTE: An Automated Alcohol Dehydrogenase Method for Ethanol Quantification
in Urine and Whole Blood,
L. Kristoffersen and A. Smith-Kielland
TECHNICAL
NOTE: Evaluation of the Post-Rotational Nystagmus Test (PRN) in
Determining Alcohol Intoxication,
M. Karlovs¹ek and Balaz¹ic
CASE
REPORT: Fatality Due to Acute a-Methyltryptamine Intoxication,
D.M. Boland, W. Andollo, G.W. Hime, and W.L. Hearn
CASE
REPORT: Distribution of GHB in Tissues and Fluids Following a
Fatal Overdose,
S. Mazarr-Proo and S. Kerrigan
CASE
REPORT: Postmortem Distribution of Tramadol, Amitriptyline, and
Their Metabolites in a Suicidal Overdose,
N.D. Bynum, J.L. Poklis, M. Gaffney-Kraft, D. Garside, and J.D.
Ropero-Miller
CASE
REPORT: Case Studies of Postmortem Quetiapine: Therapeutic or
Toxic Concentrations?
D. Parker and I. McIntyre
2004 SOFT–TIAFT Joint Meeting
Abstracts
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order this issue, click
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September 2004
SOFT Issue
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Relationship
of Δ9-Tetrahydrocannabinol Concentations in Oral Fluid and
Plasma after Controlled Administration of Smoked Cannabis
Marilyn A. Huestis and Edward J. Cone
Development
of an Analytical Approach to the Specimens Collected from Victims
of Sexual Assault
Matthew Juhascik, Ngog Lan Le, Kimberly Tomlinson, Christine Moore,
R.E. Gaensslen, and Adam Negrusz
A
General Screening and Confirmation Approach to the Analysis of
Designer Tryptamines and Phenethylamines in Blood and Urine Using
GC–EI-MS and HPLC–Electrospray-MS
Shawn P. Vorce and Jason H. Sklerov
Deposition
Characteristics of Methamphetamine and Amphetamine in Fingernail
Clippings and Hair Sections
Dong-Liang Lin, Rea-Ming Yin, Hsiu-Chuan Liu, Chung-Yi Wang, and
Ray H. Liu
Sevoflurane
Analysis in Serum by Headspace Gas Chromatography with Application
to Various Biological Matrices
David L. Burrows, Andrea Nicolaides, Gretel C. Stephens, and Kenneth
E. Ferslew
Urine
Concentrations of Fentanyl and Norfentanyl During Application
of Duragesic® Transdermal Patches
Alphonse Poklis and Ronald Backer
Urinary
Analysis of Four Testosterone Metabolites and Pregnanediol by
Gas Chromatography–Combustion–Isotope Ratio Mass Spectrometry
after Oral Administrations of Testosterone
Arnaud Maõˆtre, Christophe Saudan, Patrice Mangin, and Martial
Saugy
Metabolic
Profile of Famprofazone Following Multidose Administration
April T. Rodriguez, Sandra Valtier, and John T. Cody
Cannabis
(Marijuana) Contamination of United States and Foreign Paper Currency
Eric S. Lavins, Bethany D. Lavins, and Amanda J. Jenkins
A
Liquid Chromatographic–Electrospray-Tandem Mass Spectrometric
Method for Quantitation of Quetiapine in Human Plasma and Liver
Microsomes: Application to a Study of In Vitro Metabolism
Shen-Nan Lin, Yan Chang, David E. Moody, and Rodger L. Foltz
Enantiomeric
Separation and Quantitation of (±)-Amphetamine, (±)-Methamphetamine,
(±)-MDA, (±)-MDMA, and (±)-MDEA in Urine
Specimens by GC–EI-MS after Derivatization with (R)-(–)
or (S)-(+)-a- Methoxy-a-(trifluoromethy)phenylacetyl Chloride
(MTPA)
Buddha D. Paul, John Jemionek, David Lesser, Aaron Jacobs, and
Douglas A. Searles
An
Uncertainty Budget for the Measurement of Ethanol in Blood by
Headspace Gas Chromatography
Jesper Kristiansen and Henning Willads Petersen
A
Fatal Overdose of Cocaine Associated with Coingestion of Marijuana,
Buprenorphine and Fluoxetine. Body Fluid and Tissue Distribution
of Cocaine and Its Metabolites Determined by Hydrophilic Interaction
Chromatography–Mass Spectrometry (HILIC–MS)
Christian Giroud, Katarzyna Michaud, Frank Sporkert, Chin Eap,
Marc Augsburger, Pascal Cardinal, and Patrice Mangin
Lorazepam
and Driving Impairment
Jayne E. Clarkson, Ann Marie Gordon, and Barry K. Logan
Suspected
GHB Overdoses in the Emergency Department
Fiona J. Couper, Jayne E. Thatcher, and Barry K. Logan
Evaluation
of the Triage PPY On-Site Testing Device for the Detection of
Dextropropoxyphene in Urine
Alphonse Poklis, Justin L. Poklis, Lisa D. Tarnai, and Ronald
C. Backer
Comparison
of the Microgenics CEDIA® Heroin Metabolite (6-AM) and the
Roche Abuscreen® ONLINE Opiate Immunoassays for the Detection
of Heroin Use in Forensic Urine Samples
Justin M. Holler, Thomas Z. Bosy, Kevin L. Klette, Russel Wiegand,
John Jemionek, and Aaron Jacobs
TECHNICAL
NOTE: A High-Performance Liquid Chromatographic–Atmospheric
Pressure Chemical Ionization-Tandem Mass Spectrometric Method
for Determination of Risperidone and 9-Hydroxyrisperidone in Human
Plasma
David E. Moody, John D. Laycock, Wei Huang, and Rodger L. Foltz
TECHNICAL
NOTE: Validation of the Cozart® Microplate EIA for Cocaine
and Metabolites in Oral Fluid, Gail Cooper
Lisa Wilson, Claire Reid, Dene Baldwin, Chris Hand, and Vina Spiehler
CASE
REPORT: Two Cases Involving Clomipramine Intoxication
Joseph Avella, Michael Lehrer, Michael Katz, and Edward Minden
CASE
REPORT: Hydroxycarbazepine Distribution in Three Postmortem Cases
Barry Levine, Deborah Green-Johnson, Karla A. Moore, and David
R. Fowler
CASE
REPORT: Addicted to Driving Under the Influence—a GHB/GBL
Case Report
Fiona J. Couper and Barry K. Logan
CASE
REPORT: Hair to Document Drug-Facilitated Crimes: Four Cases Involving
Bromazepam
Marion Villain, Marjorie Ch`eze, Veronique Dumestre, Bertrand
Ludes, and Pascal Kintz
CASE
REPORT: Fatal Overdoses Associated with Quetiapine
Loralie J. Langman, Henry A. Kaliciak, and Sheila Carlyle
CASE
REPORT: A Non-Fatal Case of Sodium Toxicity
Thomas C. Kupiec, John M. Goldenring, and Vishnu Raj
CASE
REPORT: Postmortem Morphine Concentrations Following Use of a
Continuous Infusion Pump
Sarah Kerrigan, Donna Honey, and Ginger Baker
CASE
REPORT: Tissue Distribution of Molindone in a Multidrug Overdose
Dwight D. Flammia, Henry R. Bateman, Joseph J. Saady, and Erik
D. Christensen
CASE
REPORT: Metaxalone (Skelaxin®)-Related Death
Justin L. Poklis, Jeri D. Ropero-Miller, Diana Garside, and Ruth
E. Winecker
JULY/AUGUST
2004
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Editorial,
John R. Barr
Monitoring
Sulfur Mustard Exposure by Gas Chromatography–Mass Spectrometry
Analysis of Thiodiglycol Cleaved from Blood Proteins
B.R. Capacio, J.R. Smith, M.T. DeLion, D.R. Anderson, J.S.
Graham, G.E. Platoff, and W.D. Korte
Procedure
for Montoring Exposure to Sulfur Mustard Based on Modified Edman
Degradation of Globin
D. Noort, A. Fidder, H.P. Benschop, L.P.A. de Jong, and J.R. Smith
Standard
Operating Procedure for Immunuslotblot Assay for Analysis of DNA/Sulfur
Mustard Adducts in Human Blood and Skin
G.P. van der Schans, R. Mars-Groenendijk, L.P.A. de Jong, H.P.
Benschop, and D. Noort
Quantitation
of Biomarkers of Exposure to Nitrogen Mustards in Urine from Rats
Dosed with Nitrogen Mustards and from an Unexposed Human Population
S.W. Lemire, J.R. Barr, D.L. Ashley, C.T. Olson, and T.L. Hayes
Quantitation
of the Sulfur Mustard Metabolites 1,1'-Sulfonylbis[2-(methylthio)ethane]
and Thiodiglycol in Urine Using Isotope Dilution Gas Chromatography–Tandem
Mass Spectrometry
A.E. Boyer, D. Ash, D.B. Barr, C.L. Young, W.J. Driskell, R.D.
Whitehead, Jr., M. Ospina, K.E. Preston, A.R. Woolfitt, R.A. Martinez,
L.A. Silks, and J.R. Barr
Retrospective
Detection of Exposure to Sulfur Mustard: Improvements on an Assay
for Liquid Chromatography–Tandem Mass Spectrometry Analysis
of Albumin/Sulfur Mustard Adducts
D. Noort, A. Fidder, A.G. Hulst, A.R. Woolfitt, D. Ash, and J.R.
Barr
A
Rapid, Sensitive Method for the Quantitation of Specific Metabolites
of Sulfur Mustard in Human Urine Using Isotope-Dilution Gas Chromatography–Mass
Spectrometry
C.L. Young, D. Ash, W.J. Driskell, A.E. Boyer, R.A. Martinez,
L.A. Silks, and J.R. Barr
Analysis
of b-Lyase Metabolites of Sulfur Mustard in Urine by Electrospray
Liquid Chromatography–Tandem Mass Spectrometry
R.W. Read and R.M. Black
Analysis
of the Sulfur Mustard Metabolite 1,1'-Sulfonylbis[2-S-(N-acetylcysteinyl)ethane]
in Urine by Negative Ion Electrospray Liquid Chromatography–Tandem
Mass Spectrometry
R.W. Read and R.M. Black
Quantitation
of Fluoride Ion Released Sarin in Red Blood Cell Samples by Gas
Chromatography–Chemical Ionization Mass Spectrometry Using
Isotope Dilution and Large-Volume Injection
E.M. Jakubowski, J.M. McGuire, R.A. Evans, J.L. Edwards, S.W.
Hulet, B.J. Benton, J.S. Forster, D.C. Burnett, W.T. Muse, K.
Matson, C.L. Crouse, R.J. Mioduszewski, and S.A. Thomson
Improvements
of the Fluoride Reactivation Method for the Verification of Nerve
Agent Exposure
C.E.A.M. Degenhardt, K. Pleijsier, M.J. van der Schans, J.P. Langenberg,
K.E. Preston, M.I. Solano, V.L. Maggio, and J.R. Barr
Quantitation
of Metabolites of the Nerve Agents Sarin, Soman, Cyclohexylsarin,
VX, and Russian VX in Human Urine Using Isotope-Dilution Gas Chromatography–Mass
Spectrometry
J.R. Barr, W.J. Driskell, L.S. Aston, and R.A. Martinez
Identification
and Characterization of the Major Huperzine A Metabolite in Rat
Blood
G.E. Garcia, R.P. Hicks, D. Skanchy, D.R. Moorad-Doctor, B.P.
Doctor, and H.S. Ved
Gas
Chromatographic–Mass Spectrometric Determination of British
Anti-Lewisite in Plasma
C.E. Byers, E.R. Holloway, W.D. Korte, J.R. Smith, E.D. Clarkson,
G.E. Platoff, and B.R. Capacio
TECHNICAL
NOTE: Analysis of the Enantiomers of VX Using Normal-Phase Chiral
Liquid Chromatography with Atmospheric Pressure Chemical Ionization-Mass
Spectrometry
J.R. Smith
October
SOFT issue 2003
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Urine
Testing for Cocaine Abuse: Metabolic and Excretion Patterns Following
Different Routes of Administration and Methods for Detection of
False-Negative Results
Edward J. Cone, Angela Sampson-Cone, William D. Darwin, Marilyn
A. Huestis, and Jonathan M. Oyler
Sensitivity,
Specificity, and Efficiency in Detecting Opiate Use in Oral Fluid
with the Cozart® Opiate Microplate EIA and GC–MS Following
Controlled Codeine Administration
Allan J. Barnes, Insook Kim, Raf Schepers, Eric T. Moolchan, Lisa
Wilson, Gail Cooper, Claire Reid, Chris Hand, and Marilyn A. Huestis
Cozart®
RapiScan Oral Fluid Drug Testing System: An Evaluation of Sensitivity,
Specificity, and Efficiency for Cocaine Detection Compared with
ELISA and GC–MS Following Controlled Cocaine Administration
Erin A. Kolbrich, Insook Kim, Allan J. Barnes, Eric T. Moolchan,
Lisa Wilson, Gail A. Cooper, Claire Reid, Dene Beldwin, Chris
W. Hand, and Marilyn A. Huestis
Opiate
Recidivism in a Drug-Treatment Program: Comparison of Hair and
Urine Data
Bradley K. Charles, Jayme E. Day, Douglas E. Rollins, and Diana
G. Wilkins
An
Evaluation of Rapid Point-of-Collection Oral Fluid Drug-Testing
Devices
J. Michael Walsh, Ron Flegel, Dennis J. Crouch, Leo Cangianelli,
and Jakub Baudys
A
Liquid Chromatographic–Tandem Mass Spectrometric Method
for the Analysis of Serotonin and Related Indoles in Human Whole
Blood
Jonathan P. Danaceau, George M. Anderson, William M. McMahon,
and Dennis J. Crouch
Stability
of Plasma Gamma-Hydroxybutyrate Determined by Gas Chromatography–Positive
Ion Chemical Ionization-Mass Spectrometry
Meng Chen, David M. Andrenyak, David E. Moody, and Rodger L. Foltz
The
Determination of Morphine in Urine and Oral Fluid Following Ingestion
of Poppy Seeds
Timothy P. Rohrig and Christine Moore
Occupational
Cocaine Exposure of Crime Laboratory Personnel Preparing Training
Aids for a Military Working Dog Program
Jay M. Gehlhausen, Kevin L. Klette, Peter R. Stout, and JoAnn
Given
LC–MS
Analysis of 2-Oxo-3-Hydroxy LSD from Urine Using a Speedisk Positive
Pressure Processor with Cerex PolyChrom CLIN II Columns
Carl K. Horn, Kevin L. Klette, and Peter R. Stout
Analysis
of Buprenorphine, Norbuprenorphine, and Their Glucuronides in
Urine by Liquid Chromatography–Mass Spectrometry
Robert Kronstrand, Tor Seldén, and Martin Josefsson
Performance
Characteristics of Selected Immunoassays for Preliminary Test
of 3,4-Methylenedioxymethamphetamine, Methamphetamine, and Related
Drugs in Urine Specimens
Jui Hsu, Chiareiy Liu, C.P. Hsu, Wen-Ing Tsay, Jih-Heng Li, Dong-Liang
Lin, and Ray H. Liu
Metabolic
Profile of Amphetamine and Methamphetamine Following Administration
of the Drug Famprofazine
Brandy Greenhill, Sandra Valtier, and John T. Cody
Amphetamine
Enantiomer Excretion Profile Following Administration of Adderall
John T. Cody, Sandra Valtier, and Stephen L. Nelson
Postmortem
Indentification and Quantitation of 2,5-Dimethoxy-4-n-propylthiophenethylamine
Using GC–MSD and GC–NPD
Byron Curtis, Philip Kemp, Linda Harty, Chai Choi, and Dix Christensen
Fentanyl
Misuse and Abuse: A Summary of 23 Postmortem Cases
James J. Kuhlman, Jr., Rebecca McCaulley, Tara J. Valouch, and
George S. Behonick
Development
of a Rapid and Sensitive Method for the Quantitation of Benzodiazepines
in Calliphora vicina Larvae and Puparia by LC–MS–MS
M. Wood, M. Laloup, K. Pien, N. Samyn, M. Morris, R.A.A. Maes,
E.A. de Bruijn, V. Maes, and G. De Boeck
TECHNICAL
NOTE: Analysis of Fentanyl and Norfentanyl in Human Plasma by
Liquid Chromatography–Tandem Mass Spectrometry Using Electrospray
Ionization
J. Day, M. Slawson, R.A. Lugo, and D. Wilkins
TECHNICAL
NOTE: Stability of Ethanol in Postmortem Blood and Vitreous Humor
in Long-Term Refrigerated Storage
Theresa Olsen and W. Lee Hearn
TECHNICAL
NOTE: Caffeine Content of Specialty Coffees
Rachel R. McCusker, Bruce A. Goldberger, and Edward J. Cone
CASE
REPORT: Fatal Cold Medication Intoxication in an Infant
Diane M. Boland, Joseph Rein, Emma O. Lew, and W. Lee Hearn
CASE
REPORT: Buprenorphine in Drug-Facilitated Sexual Abuse: A Fatal
Case Involving a 14-Year-Old Boy
Pascal Kintz, Marion Villain, Antoine Tracqui, Vincent Cirimele,
and Bertrand Ludes
LETTER TO THE EDITOR: Evaluation of
a Solid-Phase Extraction Method for Codeine and Morphine in Urine
Using Cerex Polychrom™ Clin II Columns and the Speedisk™
48 Pressure Processor at a High-Throughput Forensic Drug-Testing
Laboratory
Melissa M. Churley, Timothy P. Lyons, Paul V. Robrandt, and Mark
R. Bruins
October
SOFT issue 2002
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Urine
Testing for Cocaine Abuse: Metabolic and Excretion Patterns Following
Different Routes of Administration and Methods for Detection of
False-Negative Results
Edward J. Cone, Angela Sampson-Cone, William D. Darwin, Marilyn
A. Huestis, and Jonathan M. Oyler
Sensitivity,
Specificity, and Efficiency in Detecting Opiate Use in Oral Fluid
with the Cozart® Opiate Microplate EIA and GC–MS Following
Controlled Codeine Administration
Allan J. Barnes, Insook Kim, Raf Schepers, Eric T. Moolchan, Lisa
Wilson, Gail Cooper, Claire Reid, Chris Hand, and Marilyn A. Huestis
Cozart®
RapiScan Oral Fluid Drug Testing System: An Evaluation of Sensitivity,
Specificity, and Efficiency for Cocaine Detection Compared with
ELISA and GC–MS Following Controlled Cocaine Administration
Erin A. Kolbrich, Insook Kim, Allan J. Barnes, Eric T. Moolchan,
Lisa Wilson, Gail A. Cooper, Claire Reid, Dene Beldwin, Chris
W. Hand, and Marilyn A. Huestis
Opiate
Recidivism in a Drug-Treatment Program: Comparison of Hair and
Urine Data
Bradley K. Charles, Jayme E. Day, Douglas E. Rollins, and Diana
G. Wilkins
An
Evaluation of Rapid Point-of-Collection Oral Fluid Drug-Testing
Devices
J. Michael Walsh, Ron Flegel, Dennis J. Crouch, Leo Cangianelli,
and Jakub Baudys
A
Liquid Chromatographic–Tandem Mass Spectrometric Method
for the Analysis of Serotonin and Related Indoles in Human Whole
Blood
Jonathan P. Danaceau, George M. Anderson, William M. McMahon,
and Dennis J. Crouch
Stability
of Plasma Gamma-Hydroxybutyrate Determined by Gas Chromatography–Positive
Ion Chemical Ionization-Mass Spectrometry
Meng Chen, David M. Andrenyak, David E. Moody, and Rodger L. Foltz
The
Determination of Morphine in Urine and Oral Fluid Following Ingestion
of Poppy Seeds
Timothy P. Rohrig and Christine Moore
Occupational
Cocaine Exposure of Crime Laboratory Personnel Preparing Training
Aids for a Military Working Dog Program
Jay M. Gehlhausen, Kevin L. Klette, Peter R. Stout, and JoAnn
Given
LC–MS
Analysis of 2-Oxo-3-Hydroxy LSD from Urine Using a Speedisk Positive
Pressure Processor with Cerex PolyChrom CLIN II Columns
Carl K. Horn, Kevin L. Klette, and Peter R. Stout
Analysis
of Buprenorphine, Norbuprenorphine, and Their Glucuronides in
Urine by Liquid Chromatography–Mass Spectrometry
Robert Kronstrand, Tor Seldén, and Martin Josefsson
Performance
Characteristics of Selected Immunoassays for Preliminary Test
of 3,4-Methylenedioxymethamphetamine, Methamphetamine, and Related
Drugs in Urine Specimens
Jui Hsu, Chiareiy Liu, C.P. Hsu, Wen-Ing Tsay, Jih-Heng Li, Dong-Liang
Lin, and Ray H. Liu
Metabolic
Profile of Amphetamine and Methamphetamine Following Administration
of the Drug Famprofazine
Brandy Greenhill, Sandra Valtier, and John T. Cody
Amphetamine
Enantiomer Excretion Profile Following Administration of Adderall
John T. Cody, Sandra Valtier, and Stephen L. Nelson
Postmortem
Indentification and Quantitation of 2,5-Dimethoxy-4-n-propylthiophenethylamine
Using GC–MSD and GC–NPD
Byron Curtis, Philip Kemp, Linda Harty, Chai Choi, and Dix Christensen
Fentanyl
Misuse and Abuse: A Summary of 23 Postmortem Cases
James J. Kuhlman, Jr., Rebecca McCaulley, Tara J. Valouch, and
George S. Behonick
Development
of a Rapid and Sensitive Method for the Quantitation of Benzodiazepines
in Calliphora vicina Larvae and Puparia by LC–MS–MS
M. Wood, M. Laloup, K. Pien, N. Samyn, M. Morris, R.A.A. Maes,
E.A. de Bruijn, V. Maes, and G. De Boeck
TECHNICAL
NOTE: Analysis of Fentanyl and Norfentanyl in Human Plasma by
Liquid Chromatography–Tandem Mass Spectrometry Using Electrospray
Ionization
J. Day, M. Slawson, R.A. Lugo, and D. Wilkins
TECHNICAL
NOTE: Stability of Ethanol in Postmortem Blood and Vitreous Humor
in Long-Term Refrigerated Storage
Theresa Olsen and W. Lee Hearn
TECHNICAL
NOTE: Caffeine Content of Specialty Coffees
Rachel R. McCusker, Bruce A. Goldberger, and Edward J. Cone
CASE
REPORT: Fatal Cold Medication Intoxication in an Infant
Diane M. Boland, Joseph Rein, Emma O. Lew, and W. Lee Hearn
CASE
REPORT: Buprenorphine in Drug-Facilitated Sexual Abuse: A Fatal
Case Involving a 14-Year-Old Boy
Pascal Kintz, Marion Villain, Antoine Tracqui, Vincent Cirimele,
and Bertrand Ludes
LETTER TO THE EDITOR: Evaluation of
a Solid-Phase Extraction Method for Codeine and Morphine in Urine
Using Cerex Polychrom™ Clin II Columns and the Speedisk™
48 Pressure Processor at a High-Throughput Forensic Drug-Testing
Laboratory
Melissa M. Churley, Timothy P. Lyons, Paul V. Robrandt, and Mark
R. Bruins
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October
SOFT issue 2002
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here
Correlation
Between Pharmacological Effects and Plasma Cocaine Concentrations
after Smoked Administration,
Amanda J. Jenkins, Robert M. Keenan, Jack E. Henningfield, and
Edward J. Cone
Urinary
Elimination of Cocaine Metabolites in Chronic Cocaine Users During
Cessation,
Kenzie L. Preston, David H. Epstein, Edward J. Cone, Abraham T.
Wtsadik, Marilyn A. Huestis, and Eric T. Moolchan
Evaluation
of a Solid-Phase Extraction Method for Benzoylecgonine Urine Analysis
in a High-Throughput Forensic Urine Drug-Testing Laboratory,
Peter R. Stout, Jay M. Gehlhausen, Carl K. Horn, and Kevin L.
Klette
Storage
Stability of Simulator Ethanol Solutions for Vapor-Alcohol Control
Tests in Breath-Alcohol Analysis,
Kurt M. Dubowski, Emmett E. Goodson, and McBeth Sample, Jr.
Improved
Screen and Confirmation Test of 7-Aminoflunitrazepam in Urine
Specimens for Monitoring Flunitrazepam (Rohypnol) Exposure,
Perng-Haur Wang, Chiareiy Liu, Wen-Ing Tsay, Jih-Heng Li, Ray
H. Liu, Tai-Guang Wu, Wen-Jing Cheng, Dong-Liang Lin, Tsun-Ying
Huang, and Cheng-Hsing Chen
The
Defined HHS/DOT Substituted Urine Criteria Validated Through a
Controlled Hydration Study,
Kenneth Edgell, Yale H. Caplan, Leon R. Glass, and Janine Denis
Cook
Evaluation
of Freezing Point Depression Osmolality for Classifying Random
Urine Specimens Defined as Substituted Under HHS/DOT Criteria,
Janine Denis Cook, Mark W. Hannon, Sr., Tamdan Vo, and Yale H.
Caplan
Quantitative
Analysis of Selegiline and Three Metabolites (N-Desmethylselegiline,
Methamphetamine, and Amphetamine) in Human Plasma by High-Performance
Liquid Chromatography–Atmospheric Pressure Chemical Ionization-Tandem
Mass Spectrometry,
Matthew H. Slawson, James L. Taccogno, Rodger L. Foltz, and David
E. Moody
Pharmacogenomics
as Molecular Autopsy for Postmortem Forensic Toxicology: Genotyping
Cytochrome P450 2D6 for Oxycodone Cases,
Paul J. Jannetto, Steven H. Wong, Susan B. Gock, Elvan Laleli-Sahin,
B. Charles Schur, and Jeffrey M. Jentzen
Oxycontin®:
The Concept of a “Ghost Pill” and the Postmortem Tissue
Distribution of Oxycodone in 36 Cases,
Daniel T. Anderson, Kristina L. Fritz, and Joseph J. Muto
Effects
of Oxidizing Adulterants on Detection of 11-Nor-Δ9-THC-Carboxylic
Acid in Urine,
Buddha D. Paul and Aaron Jacobs
Performance
Evaluation of Three On-Site Adulterant Detection Devices for Urine
Specimens,
Michelle R. Peace and Lisa D. Tarnai
Deposition
of 7-Aminoclonazepam and Clonazepam in Hair Following a Single
Dose of Klonopin™,
Adam Negrusz, Andrew M. Bowen, Christine M. Moore, Sheila M. Dowd,
Mary Jane Strong, and Philip G. Janicak
Segmental
Ion Spray LC–MS–MS Analysis of Benzodiazepines in
Hair of Psychiatric Patients,
Robert Kronstrand, Ingrid Nyström, Martin Josefsson, and
Sheilagh Hodgins
An
Evaluation of Two Wash Procedures for the Differentiation of External
Contamination versus Ingestion in the Analysis of Human Hair Samples
for Cocaine,
Michael I. Schaffer, Wen-Ling Wang, and John Irving
Detection
of Cocaine Analytes and Opiates in Nails Postmortem Cases,
David A. Engelhart and Amanda J. Jenkins
A
Field Evaluation of Five On-Site Drug-Testing Devices,
Dennis J. Crouch, Rebekah K. Hersch, Royer F. Cook, James F. Frank,
and J. Michael Walsh
An
Evaluation of the OnTrak Testcup®-er On-Site Urine Drug Testing
Device for Drugs Commonly Encountered in Emergency Departments,
Michelle R. Peace, Justin L. Poklis, Lisa D. Tarnai, and Alphonse
Poklis
Validation
of a Microtiter Plate ELISA for Screening of Postmortem Blood
for Opiates and Benzodiazepines,
Philip Kemp, Gary Sneed, Tom Kupiec, and Vina Spiehler
Choice
of an ELISA Assay for Screening Postmortem Blood for Amphetamine
and/or Methamphetamine,
Tom Kupiec, Lacinda DeCicco, Vina Spiehler, Gary Sneed, and Philip
Kemp
Comparison
of EMIT®II, CEDIA®, and DPC® RIA Assays for the Detection
of Lysergic Acid Diethylamide in Forensic Urine Samples,
Russell F. Wiegand, Kevin L. Klette, Peter R. Stout, and Jay M.
Gehlhausen
TECHNICAL
NOTE: Simultaneous Quantitation of Opioids in Blood by GC–EI-MS
Analysis Following Deproteination, Detautomerization of Keto Analytes,
Solid-Phase Extraction, and Trimethylsilyl Derivatization,
Jeri D. Ropero-Miller, Matthew K. Lambing, and Ruth E. Winecker
CASE
REPORT: Blood Investigation in a Fatality Involving the Veterinary
Drug T-61,
P. Kintz, V. Cirimele, and B. Ludes
CASE
REPORT: Death by Paint Thinner,
Ines Collison and Wayne Moorehead
LETTER
TO THE EDITOR: Differentiation of the 2,3-Methylenedioxy Regioisomer
of 3,4-MDMA (Ecstasy) by Gas Chromatography–Mass Spectrometry
John T. Cody and Sandra Valtier
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October
2001 Special Issue: Society of Forensic Toxicologists, Inc.
To order this issue, click
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Effect
of Four Laboratory Decontamination Procedures on the Quantitative
Determination of Cocaine and Metabolites in Hair by HPLCMS
Ryan B. Paulsen, Diana G. Wilkins, Matthew H. Slawson, Kimberly
Shaw, and Douglas E. Rollins
A
Validated Liquid ChromatographyAtmospheric Pressure Chemical
Ionization-Tandem Mass Spectrometry Method for Quantitation of
Cocaine and Benzoylecgonine in Human Plasma
Shen-Nan Lin, David E. Moody, George E. Bigelow, and Rodger L.
Foltz
Urinary
Excretion Profiles for Total Morphine, Free Morphine, and 6-Acetylmorphine
Following Smoked and Intravenous Heroin
Michael L. Smith, Eric T. Shimomura, Jacquelyn Summers, Buddha
D. Paul, Amanda J. Jenkins, W. David Darwin, and Edward J. Cone
Detection
of Opiate Use in a Methadone Maintenance Treatment Population
with the CEDIA® 6-Acetylmorphine and CEDIA DAU Opiate Assays
Alan C. Spanbauer, Scott Casseday, David Davoudzadeh, Kenzie L.
Preston, and Marilyn A. Huestis
Gas
ChromatographyMass Spectrometry Confirmation of Cozart RapiScan
Saliva Methadone and Opiate Tests
Lesley Moore, John Wicks, Vina Spiehler, and Richard Holgate
Cathinone
(Khat) and Methcathinone (CAT) in Urine Specimens: A Gas ChromatographicMass
Spectrometric Detection Procedure
Buddha D. Paul and Kenneth A. Cole
Simultaneous
Determination of D9-Tetrahydrocannabinol
and 11-nor-9-Carboxy-D9-Tetrahydrocannabinol
in Human Plasma by Solid-Phase Extaction and Gas ChromatographyNegative
Ion Chemical Ionization-Mass Spectrometry
Wei Huang, David E. Moody, David M. Andrenyak, Elizabeth K. Smith,
Rodger L. Foltz, Marilyn A. Huestis, and John F. Newton
Temporal
Indication of Marijuana Use Can Be Estimated from Plasma and Urine
Concentrations of D9-Tetrahydrocannabinol,
11-Hydroxy-D9-Tetrahydrocannabinol,
and 11-nor-Æ9-Tetrahydrocannabinol-9-Carboxylic Acid
Joseph E. Manno, Barbara R. Manno, Philip M. Kemp, Dempsey D.
Alford, Imad K. Abukhalaf, Mary E. McWilliams, Frances N. Hagaman,
and Mary Jo Fitzgerald
Solid-Phase
Extraction and GCMS Analysis of THC-COOH Method Optimized
for a High-Throughput Forensic Drug-Testing Laboratory
Peter R. Stout, Carl K. Horn, and Kevin L Klette
The
Determination of 11-nor-D9-Tetrahydrocannabinol-9-Carboxylic
Acid (THC-COOH) in Hair using Negative Ion Gas ChromatographyMass
Spectrometry and High-Volume Injection
Christine Moore, Frank Guzaldo, and Thomas Donahue
A
Comparison of Roche Kinetic Interaction of Microparticles in Solution
(KIMS®) Assay for Cannabinoids and GCMS Analysis for
11-nor-9-Carboxy-D9-Tetrahydrocannabinol
Timothy P. Lyons, Catherine K. Okano, Judith A. Kuhnle, Mark R.
Bruins, William D. Darwin, Eric T. Moolchan, and Marilyn A. Huestis
D9-Tetrahydrocannabivarin
as a Marker for the Ingestion of Marijuana versus Marinol®:
Results of a Clinical Study
Mahmoud A. ElSohly, Harriet deWit, Stephen R. Wachtel, and Timothy
P. Murphy
Analysis
of Morphine and Codeine in Samples Adulterated with Stealth
John T. Cody, Sandra Valtier, and James Kuhlman
Application
of a Convenient Extraction Procedure for the Analysis of Gamma-Hydroxybutyric
Acid in Fatalities Involving Gamma-Hydroxybutyric Acid, Gamma-Butyrolactone,
and 1,4-Butanediol
W.C. Duer, K.L. Byers, and J.V. Martin
Urine
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Hydrolysis
of Conjugated Metabolites of Buprenorphine. I. The Quantitative
Enzymatic Hydrolysis of Buprenorphine-3-b-D-Glucuronide in Human
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Shixia Feng, Mahmoud A. ElSohly, and David T. Duckworth
Incorporation
of Selegiline Metabolites into Hair after Oral Selegiline Intake
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Development
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Diane M. Boland, M |