2008

January/February | March | April | May/June

January/February 2008

Editorial, John R. Barr

An Overview of Biological Markers of Exposure to Chemical Warfare Agents,
Robin M. Black

Analysis of Urinary Metabolites of Sulfur Mustard in Two Individuals after Accidental Exposure,
John R. Barr, Carrie L. Pierce, J. Richard Smith, Benedict R. Capacio, Adrian R. Woolfitt, Maria I. Solano, Joe V. Wooten, Sharon W. Lemire, Jerry D. Thomas, Doris H. Ash, and David L. Ashley

Analysis for Plasma Protein Biomarkers Following an Accidental Human Exposure to Sulfur Mustard,
J. Richard Smith, Benedict R. Capacio, William D. Korte, Adrian R. Woolfitt, and John R. Barr

Retrospective Detection of Sulfur Mustard Exposure by Mass Spectrometric Analysis of Adducts to Albumin and Hemoglobin: An In Vivo Study,
D. Noort, A. Fidder, C.E.A.M. Degenhardt-Langelaan, and A.G. Hulst

Improvements in the Methodology of Monitoring Sulfur Mustard Exposure by Gas Chromatography–Mass Spectrometry Analysis of Cleaved and Derivatized Blood Protein Adducts,
Richard J. Lawrence, J. Richard Smith, Brian L. Boyd, and Benedict R. Capacio

Gas Chromatographic–Mass Spectrometric Analysis of Sulfur Mustard-Plasma Protein Adducts: Validation and Use in a Rat Inhalation Model,
Benedict R. Capacio, J. Richard Smith, Richard J. Lawrence, Brian L. Boyd, Alicia M. Witriol, Michele L. Conti, Jennifer L. Collins, and Alfred M. Sciuto

Multianalyte Quantification of Five Sesqui- and Ethyl Ether Oxy-Mustard Metabolites in Human Urine by Liquid Chromatography–Atmospheric Pressure Chemical Ionization Tandem Mass Spectrometry,
Doris H. Ash, Sharon W. Lemire, Sara C. McGrath, Lisa G. McWilliams, and John R. Barr

Development of a Liquid Chromatography–Multiple Reaction Monitoring Procedure for Concurrent Verification of Exposure to Different Forms of Mustard Agents,
Thong-Hiang Yeo, Mer-Lin Ho, and Weng-Keong Loke

Gas Chromatography–Tandem Mass Spectrometry Analysis of Red Blood Cells from Göttingen Minipig® following Whole-Body Vapor Exposure to VX,
C.E. Byers, J.M. McGuire, S.W. Hulet, D.C. Burnett, B.I. Gaviola, E.M. Jakubowski, and S.A. Thomson

A Rapid and Sensitive Technique for Assessing Exposure to VX via GC–MS–MS Analysis,
Jeffrey M. McGuire, Christopher E. Byers, Stanley W. Hulet, Edward M. Jakubowski, and Sandra A. Thomson

Quantification of Nerve Agent VX-Butyrylcholinesterase Adduct Biomarker from an Accidental Exposure,
Maria I. Solano, Jerry Thomas, James T. Taylor, Jeffrey M. McGuire, Edward. M. Jakubowski, Sandra A. Thomson, Vincent L. Maggio, Kerry E. Holland, J. Richard Smith, Benedict Capacio, Adrian R. Woolfitt, David L. Ashley, and John R. Barr

Determination of VX-G Analogue in Red Blood Cells via Gas Chromatography–Tandem Mass Spectrometry Following an Accidental Exposure to VX,
Jeffrey M. McGuire, James T. Taylor, Christopher E. Byers, Edward M. Jakubowski, and Sandra A. Thomson

Quantification of Sarin and Cyclosarin Metabolites Isopropyl Methylphosphonic Acid and Cyclohexyl Methylphosphonic Acid in Minipig Plasma Using Isotope-Dilution and Liquid Chromatography–Time of Flight Mass Spectrometry,
R.A. Evans, E.M. Jakubowski, W.T. Muse, K. Matson, S.W. Hulet, R.J. Mioduszewski, S.A. Thomson, A.L. Totura, J.A. Renner, and C.L. Crouse

A Gas Chromatographic–Mass Spectrometric Approach to Examining Stereoselective Interaction of Human Serum Proteins with Soman,
David T. Yeung, J. Richard Smith, Richard E. Sweeney, David E. Lenz, and Douglas M. Cerasoli

Validation and Application of a Gas Chromatography–Mass Spectrometry Method for Determining Soman Concentration in Rat Plasma Following Low-Level Vapor Exposure,
Julie A. Renner, Paul A. Dabisch, Ronald A. Evans, Jeffrey M. McGuire, Allison L. Totura, Edward M. Jakubowski, and Sandra A. Thomson

3-Chlorotyrosine and 3,5-Dichlorotyrosine as Biomarkers of Respiratory Tract Exposure to Chlorine Gas,
Mark A. Sochaski, Annie M. Jarabek, John Murphy, and Melvin E. Andersen

A Rapid, Cost-Effective Method for Analyzing Organophosphorus Pesticide Metabolites in Human Urine for Counter-Terrorism Response,
Gayanga Weerasekera, Kimberly D. Smith, Larry L. Needham, and Dana B. Barr

Modifications to the Organophosphorus Nerve Agent-Butyrylcholinesterase Adduct Refluoridation Method for Retrospective Analysis of Nerve Agent Exposures,
Kerry E. Holland, Maria I. Solano, Rudolph C. Johnson, Vincent L. Maggio, and John R. Barr

Verification of Exposure to Cholinesterases Inhibitors: Generic Detection of Schedule 1 Nerve Agent Adducts to Human Butyrylcholinesterase,
M.J. van der Schans, A. Fidder, D. van Oeveren, A.G. Hulst, and D. Noort

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March 2008

Optimization of an LC–MS Method for the Determination of Artesunate and Dihydroartemisinin Plasma Levels using Liquid–Liquid Extraction
Stijn A.A. Van Quekelberghe, Shahid A. Soomro, Jan A. Cordonnier, and F. Herwig Jansen

Accumulation, Fractionation, and Analysis of Platinum in Toxicologically Affected Tissues after Cisplatin
Oxaliplatin, and Carboplatin Administration, D. Esteban-Fernández, J.M. Verdaguer, R. Ramírez-Camacho, M.A. Palacios, M.M. Gómez-Gómez

Quantitation of Seven Low-Dosage Antipsychotic Drugs in Human Postmortem Blood Using LC–MS–MS
M. Roman, R. Kronstrand, D. Lindstedt, and M. Josefsson

Ethanol Contamination Leads to Fatty Acid Ethyl Esters in Hair Samples
Nadia De Giovanni, Giuseppe Donadio, and Marcello Chiarotti

Cannabinoid Concentrations in Spot Serum Samples 24–48 Hours After Discontinuation of Cannabis Smoking
Gisela Skopp and Lucia Pötsch

A Comparison of Methadone, Oxycodone, and Hydrocodone Related Deaths in Northeast Ohio
Daniel D. Baker and Amanda J. Jenkins

Investigation of the First Deaths in the United Kingdom Involving the Detection and Quantitation of the Piperazines BZP and 3-TFMPP
Simon Elliott and Christopher Smith

SHORT COMMUNICATION: CYP2D6 Ultrarapid Metabolism and Morphine/Codeine Ratios in Blood: Was it Codeine or Heroin?
Y.J. He, J. Brockmöller, H. Schmidt, I. Roots, and J. Kirchheiner

CASE REPORT: An Unusual Trichloroethanol Fatality Attributed to Sniffing Trichloroethylene
Graham R. Jones and Peter P. Singer

CASE REPORT: A Fatal Intoxication from Ingestion of 2-Methyl-4-chlorophenoxyacetic Acid (MCPA), Tatsunori Takayasu
Takahito Hayashi, Yuko Ishida, Mizuho Nosaka, Shinya Mizunuma, Tomoko Miyashita, Mariko Kawaguchi, Akihiko Kimura, and Toshikazu Kondo

CASE REPORT: A Fatal Case of Bupropion (Zyban®) Overdose, Magali Mercerolle,
Raphaël Denooz, Gérard Lachâtre, and Corinne Charlier

LETTER TO THE EDITOR: Elimination Half-Lives of Benzoylecgonine and MDMA in an Apprehended Driver
A.W. Jones

April 2008

April 2008

201 In Vivo Versus In Vitro Airway Surface Liquid Nicotine Levels Following Cigarette Smoke Exposure,
Lucy A. Clunes, Arlene Bridges, Neil Alexis, and Robert Tarran

208 An Enantiomer-Selective Liquid C hromatography–Tandem Mass Spectrometry Method for Methadone and EDDP Validated for Use in Human Plasma, Urine,
and Liver Microsomes, David E. Moody, Shen-Nan Lin, Yan Chang, Lolita Lamm, Mark K. Greenwald, and Mahmoud S. Ahmed

220 Development and Validation of ELISA and GC–MS Procedures for the Quantification of Dextromethorphan and its Main Metabolite Dextrorphan in Urine and Oral Fluid,
Warren Rodrigues, Guohong Wang, Christine Moore, Alpana Agrawal, Michael J. Vincent, and James R. Soares

227 Development and Clinical Application of an LC–MS–MS Method for Mescaline in Urine,
Kristian Björnstad, Anders Helander, and Olof Beck

232 Analysis of Confiscated Black Market Drugs Using Chromatographic and Mass Spectrometric Approaches,
Mario Thevis, Yvonne Schrader, Andreas Thomas,
Gerd Sigmund, Hans Geyer, and Wilhelm Schänzer

241 Formic Acid and Methanol Concentrations in Death Investigations,
H. Rachelle Wallage and James H. Watterson

248 Determination of Lovastatin Hydroxy Acid in Female B6C3F1 Mouse Serum,
Jon W. Lodge, Brenda L. Fletcher, Sherri S. Brown, Angela J. Parham, Reshan A. Fernando, and Bradley J. Collins

253 Simultaneous Determination of Ketamine, Tramadol, Methadone, and their Metabolites in Urine by Gas Chromatography–Mass Spectrometry,
Pai-Sheng Cheng, Choung-Huei Lee, Chiareiy Liu, and Chun-Sheng Chien

260 CASE REPORT: Determination of Fentanyl in Sweat and Hair of a Patient using Transdermal Patches, ,
Serge Schneider, Zahra Ait-m-bark, Claude Schummer Patrick Lemmer, Michel Yegles, Brice Appenzeller, and Robert Wennig

June 2008

329 Comparison of Ordinary, Weighted, and Generalized Least-Squares Straight-Line Calibrations for LC–MS–MS, GC–MS, HPLC, GC, and Enzymatic Assay,
Wayne C. Duer, Paul J. Ogren, Alison Meetze, Chester J. Kitchen, Ryan Von Lindern, Dustin C. Yaworsky, Christopher Boden, and Jeffery A. Gayer

339 Effect of Tramadol Use on Three Point-of-Care and One Instrument-Based Immunoassays for Urine Buprenorphine,
Salima Shaikh, Mindy J. Hull, Kenneth A. Bishop, David A. Griggs, William H. Long, Andrea L. Nixon, and James G. Flood

344 Arsenic Speciation of Arsine-Exposed Blood Samples by High-Performance Liquid Chromatography–Inductively Coupled Plasma Mass Spectrometry and As-Adduct, A Possible Indicator of AsH3 Exposure,
Yoshiyasu Higashikawa, Yuko Kazui, Shinichi Suzuki, and Osamu Ohtsuru

349 Determination of Cannabinoids in Whole Blood by UPLC–MS–MS,
Carole Jamey, Esther Szwarc, Antoine Tracqui, and Bertrand Ludes

355 A New Method for Simultaneous Determination of Cyclic Antidepressants and their Metabolites in Urine Using Enzymatic Hydrolysis and Fast GC–MS,
Sumandeep Rana, Victor P. Uralets, and Wayne Ross

364 Drug Screening of Hair by Liquid Chromatography–Tandem Mass Spectrometry,
S. Hegstad, H.Z. Khiabani, L. Kristoffersen, N. Kunøe, P.P. Lobmaier, and A.S. Christophersen

373 Drug Monitoring and Toxicology: A Simple Procedure for the Monitoring of Felbamate by HPLC–UV Detection,
Peter H. Tang

379 Determination of Volatile Organic Compounds in Biological Samples Using Headspace Solid-Phase Microextraction and Gas Chromatography: Toluene and Styrene,
Radhika Barua, Lai-Har Chi, Richard Fitzpatrick, Douglas Gillard, and Paul J. Kostyniak

387 SHORT COMMUNICATION: Detection of Urinary Metabolites Common to Structurally Related 17α-Alkyl Anabolic Steroids in the Horse and Application to Doping Tests in Racehorses: Methandienone, Methandriol, and Oxymetholone,
Masayuki Yamada, Sugako Aramaki, Masahiko Kurosawa, Koichi Saito, and Hiroyuki Nakazawa

392 LETTER TO THE EDITOR: Error in the Article: “Driving Under the Influence of Opiates: Concentration Relationships Between Morphine, Codeine, 6-Acetyl Morphine, and Ethyl Morphine in Blood”,
I. Papoutsis and S. Athanaselis

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