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Published:
Journal of Analytical Toxicology,
ISSN 0146-4760,
Volume 27, Number 2, March 2003,
pp. 110-112
CASE REPORT: Tissue Distribution of Xylazine in a Suicide
by Hanging
Karla A. Moore*, Mary G. Ripple, Saffia Sakinedzad, Barry Levine, and
David R. Fowler
Office of the Chief Medical Examiner, State of Maryland, 111 Penn Street, Baltimore,
Maryland 21201
Xylazine (Rompun®, Sedazine®, AnaSed®)
is currently the most commonly used sedative-analgesic in veterinary medicine.
There are nine published cases of xylazine’s involvement in human drug-related
deaths and impairment. However, blood concentrations were reported in only four
of these cases. Three of these nine cases were fatalities involving xylazine,
two of which involved xylazine alone but did not report blood concentrations
because of extensive decomposition of the bodies. This report documents a case
in which xylazine alone was identified in a suicide by hanging. The following
xylazine concentrations were found: 2.3 mg/L in heart blood; 2.9 mg/L in peripheral
(subclavian) blood; 6.3 mg/L in bile; 0.01 mg/L in urine; 6.1 mg/kg in liver;
and 7.8 mg/kg in kidney. Reproduction
of editorial content of this journal is prohibited without publisher’s
permission.
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