Published: Journal of Analytical Toxicology, ISSN 0146-4760, Volume 27, Number 5, July/August, pp. 313-317

CASE REPORT: Foxy, a Designer Tryptamine Hallucinogen
Robert Meatherall[1] and Pankaj Sharma[2]
[1]Laboratory Medicine, St. Boniface General Hospital, Winnipeg, Manitoba, Canada and
[2]Emergency Department, Victoria General Hospital, Winnipeg, Manitoba, Canada

Foxy is slang for 5-methoxy-N,N-diisopropyltryptamine. It has hallucinogenic properties, similar to other tryptamine compounds, and is mildly euphoric. This case report describes a 21-year-old Caucasian man who ingested a pill called Foxy containing an unknown amount of drug. He was observed in hospital for 2 h, during which time he had mild hallucinations and could not move his limbs. A urine sample was collected approximately 4 h after drug ingestion. The patient was then discharged with no follow up assessment. The 5-methoxy-N,N-diisopropyltryptamine was identified in the urine by gas chromatography–mass spectrometry. Standards prepared from the pure material were used in the identification. Quantitative analysis using the same analytical technique resulted in a urinary concentration of 1.7 µg/mL. Through oxidative deamination, the metabolite, 5-methoxy-indole acetic acid, was formed. It was identified in the urine, and the concentration was determined to be 1.3 µg/mL using gas chromatography–mass spectrometry. Two other compounds were discovered in the urine sample as a result of a routine drug screen. From their mass spectra, they were tentatively identified as 5-methoxy-N-isopropyltryptamine and 5-methoxy-N,N-diisopropyltryptamine-N'-oxide.

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