Published: Journal of Analytical Toxicology, ISSN 0146-4760, Volume 27, Number 5, July/August, pp. 309-312
TECHNICAL NOTE: Direct Analysis
of Plasticizers in Aqueous Samples by Atmospheric Pressure Chemical Ionization-Tandem
Mass Spectrometry (APCI-MS–MS)
The widespread manufacture of plastics requires the similarly ubiquitous use of plasticizers. Plasticizers such as bis(2-ethylhexyl) adipate (DOA) and bis(2-ethylhexyl) phthalate (DOP) enhance polymer strength and flexibility and are found in polymeric products such as cosmetics, detergents, and building and storage products (1). However, these additives are not bound to the polymer matrix and are subject to leaching. A recent Health Canada report warned that DOP may leach from medical devices and cause harm to infants, young boys, pregnant women, and nursing mothers (2). The United States Environmental Protection Agency (U.S. EPA) estimates that over 450,000 pounds of DOA were released to land and water during the period of 1987–1993 (3).
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