| |
Published:
Journal of Analytical Toxicology,
ISSN 0146-4760,
Volume 25, Number 7, October, pp. 652-656
CASE REPORT: A Contemporaneous Finding of Fenproporex in
a Polydrug Suicide
Ronald R. Bell[1], Susan B. Crookham[2], William
A. Dunn[2], Kirk M. Grates[1], and Tina M. Reiber[2]
[1]Office of the Medical Examiner, District Six, 10850 Ulmerton Road, Largo,
Florida 33778 and [2]National Medical Services, Inc., 3701 Welsh Road, Willow
Grove, Pennsylvania 19090
Fenproporex is a sympathomimetic agent with a pharmacological
profile similar to that of amphetamine. It is available in many countries throughout
the world, but it is currently not available in the United States. Because of
its stimulant effects, it has a great potential for abuse. To the best of our
knowledge, there have been no literature reports of blood or serum concentrations
found in therapeutic, toxic, or fatal cases. We report a case where fenproporex
was a finding in the death of a young adult. Blood, urine, and gastric contents
were analyzed. The following drug concentrations were found: 0.90 mg/L (inferior
vena cava blood), 1.2 mg/L (urine), and 120 mg total (gastric) for fenproporex
and 0.084 mg/L (inferior vena cava blood), 0.94 mg/L (urine), and 0.14 mg total
(gastric) for amphetamine. In addition to the fenproporex, other medications
detected and their blood concentrations found in this case were diazepam (0.54
mg/L), nordiazepam (0.46 mg/L), diphenhydramine (0.12 mg/L), and gamma hydroxybutyric
acid (GHB) (1100 mg/L).
Reproduction
of editorial content of this journal is prohibited without publisher’s
permission.
This
article is available in its entirety by fax for $40.00 each.
Visa, MasterCard and AMEX accepted.
To
order electronically click here
or call: 847-647-2900 ext. 1323
or fax request to: 847-647-1155.
To order multiple copies click here.
Please indicate JAT
volume and issue along with page numbers. |
|
Home | Subscribe
| Current Issue | Back Issues
| Search | Advertise | Other Publications
| |
