| |
Published:
Journal of Analytical Toxicology,
ISSN 0146-4760,
Volume 25,
Number 1, January/February,
pp. 26-30
FT-IR
Breath Test in the Diagnosis and Control of Treatment of Methanol Intoxications
Olli
Laakso[1], Matti Haapala[2], Petri Jaakkola[3], Reijo Laaksonen[4],[5], Kimmo
Luomanmäki[6], Janne Nieminen[2], Mika Pettersson[2], Hannu Päivä[5],
Markku Räsänen[2], and Jaakko-Juhani Himberg[7]
[1]Department of Anesthesiology, University of Helsinki, Finland; [2]Laboratory
of Physical Chemistry, University of Helsinki, Finland; [3]Temet Instruments
Oy, Helsinki, Finland; [4]Department of Clinical Pharmacology, University of
Helsinki, Finland; [5]Department of Medicine, Tampere University Hospital, Finland;
[6]Department of Medicine, Helsinki University Central Hospital, Finland; and
[7]HUCH Laboratory, Helsinki University Central Hospital, Finland
A portable
Fourier transform infrared (FT-IR) multicomponent point-of-care analyzer was
tested for the diagnosis of methanol intoxications. Breath analysis with FT-IR
was fast and easy, and no sample preparation was needed. The analyzer was adequately
sensitive and accurate in detecting and quantitating clinically relevant amounts
of ethanol and methanol in the breath of seriously ill patients. FT-IR spectrometry
was also suitable for nearly on-line monitoring of the exhaled ethanol and methanol
during hemodialysis. The breath analysis results correlated well with blood
samples. The FT-IR method used also has a traceable calibration to physical
properties of the analyte, and the measured spectra can be saved for later analysis.
Reproduction
of editorial content of this journal is prohibited without publisher’s
permission.
This
article is available in its entirety by fax for $40.00 each.
Visa, MasterCard and AMEX accepted.
To
order electronically click here
or call: 847-647-2900 ext. 1323
or fax request to: 847-647-1155.
To order multiple copies click here.
Please indicate JAT
volume and issue along with page numbers. |
|
Home | Subscribe
| Current Issue | Back Issues
| Search | Advertise | Other Publications
| |
