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Published:
Journal of Analytical Toxicology,
ISSN 0146-4760,
Volume 24,
Number 6, September 2000, pp. 450-452
Here is where the title stuff goes
Short Communication—Retrospective Study of Urinalysis for dl-Amphetamine
and dl-Methamphetamine Analysis under Current Department of Defense Guidelines
Ronald L. Shippee[1] and Donald J. Kippenberger[2]
[1]U.S. Army Forensic Toxicology Drug Testing Laboratory, 2490 Wilson
Street, Fort Meade, Maryland 20755 and
[2]Research Dynamics, Inc., 1355 Central Parkway South, Suite 100, San Antonio,
Texas 78232
Under current Department of Defense (DOD) directive, the
laboratories certified to conduct urinalyis testing in support of the DOD Drug
Deterrence Program are required to conduct dl-isomer analysis on all specimens
that confirm at a concentration greater than 500 ng/mL methamphetamine (METH).
Although the same cutoff concentration is required for amphetamine (AMP) reporting,
there is no requirement for dl-isomer analysis of AMP-positive specimens. Of
the 894,823 specimens screened by the Army Drug Testing Laboratory at Ft. Meade,
MD during a 19-month period, 339 confirmed positive for METH. From this positive
population, seven specimens failed to confirm at or above the DOD cutoff of
> 20% d-isomer. One of the seven specimens contained 534 ng/mL l-AMP and
was reported positive for AMP. Although 100% of the AMP was the l-isomer, under
current DOD directive, this information was not passed along to the Medical
Review Officers (MRO) to assist them during the interview process. Although
this situation appears to be a rare event, consideration should be given to
requiring dl-isomer analysis of AMP-positive specimens and forwarding this information
to the MRO. Reproduction
of editorial content of this journal is prohibited without publisher’s
permission.
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