Titles listed in order of publication—
January/February 2000
Page Title
1 Determination of g-Hydroxybutyrate (GHB) in Biological Specimens by Gas ChromatographyÐMass Spectrometry Ê
8 Elimination Half-Life of Acetone in Humans: Case Reports and Review of the Literature Ê
11 Rapid Analysis of Amphetamine, Methamphetamine, MDA, and MDMA in Urine Using Solid-Phase Microextraction, Direct On-Fiber Derivatization, and Analysis by GCÐMS Ê
17 Structural Elucidation of an Uncommon Phenylethylamine Analogue in Urine Responsible for Discordant Amphetamine Immunoassay Results
22 Tetrachloroethylene and Trichloroethylene Fatality: Case Report and Simple Headspace SPMEÐCapillary Gas Chromatographic Determination in Tissues
27 Elimination of the Interferences by Keto-Opiates in the GCÐMS Analysis of 6-Monoacetylmorphine
32 Identification of the General Unknown. Application of Mass Selective Detectors in Forensic Toxicology
37 Rapid Method for the Solid-Phase Extraction and GCÐMS Analysis of Flunitrazepam and Its Major Metabolites
46 Quantitative Screening for Benzodiazepines in Blood by Dual-Column Gas Chromatography and Comparison of the Results with Urine Immunoassay
54 A Comparison of Sodium Hydroxide and Sodium Sulfide Digestion of Mouse Hair in the Recovery of Radioactivity Following Systemic Administration of [3H]-Nicotine and [3H]-Flunitrazepam
59 Cocaine, Cocaine Metabolite, and Ethanol Concentrations in Postmortem Blood and Vitreous Humor
66 Use of Solid-Phase Microextraction (SPME) for the Determination of Methadone and Its Main Metabolite, EDDP, in Plasma by Gas ChromatographyÐMass Spectrometry
70 LETTER TO THE EDITOR: Saliva/Plasma Ratio of Methadone and EDDP
73 LETTER TO THE EDITOR: Æ9-Tetrahydrocannabivarin (THCV) as a Marker of Cannabis Use: Is the Methodology Forensically Acceptable?

March/April 1999

Page Title
77 Analysis of Underivatized Amphetamines and Related Phenethylamines with High-Performance Liquid ChromatographyÐAtmospheric Pressure Chemical Ionization Mass Spectrometry
85 Fatal Poisoning With a New Phenylethylamine: 4-Methylthioamphetamine (4-MTA)
90 Fatal Aluminum Phosphide Poisoning
93 Solid-Phase Microextraction in the Determination of Methadone in Human Saliva by Gas ChromatographyÐMass Spectrometry
97 SPEC¨ Disc Solid-Phase Extraction for Rapid Broad-Spectrum Drug Screening in Urine
102 Evaluation of Testosterone/Epitestosterone Ratio Influential Factors as Determined in Doping Analysis
116 Quantitative Determination of Paraquat in a Fatal Intoxication by HPLCÐDAD following Chemical Reduction with Sodium Borohydride
122 GCD Quantitation of Opiates as Propionyl Derivatives in Blood
127 The Determination of Æ9-Tetrahydrocannabinol and 11-Nor-9-Carboxy-Æ9-tetrahydrocannabinol in Whole Blood Using Solvent Extraction Combined with Polar Solid-Phase Extraction
133 Urinary Excretion of Codeine and Morphine following the Administration of Codeine-Containing Cold Syrup
140 Interpretation and Enantiomer Analysis of Methamphetamine AbusersÕ Urine and Illegally Brewed Methamphetamine Crystals
146 Determination of b2-Agonists in Bovine Urine: Comparison of Two Extraction/Clean-Up Procedures for High-Resolution Gas ChromatographyÐMass Spectrometry Analysis
153 LETTER TO THE EDITOR: Redistribution of Methamphetamine in the Early Postmortem Period
157 Acute Metobromuron Poisoning with Severe Associated Methemoglobinemia. Identification of Four Metabolites in Plasma and Urine by LCÐDAD, LCÐESI-MS, and LCÐESI-MSÐMS
165 Sensitive and Selective Determination of Tetracaine and Its Metabolite in Human Samples by Gas ChromatographyÐMass Spectrometry
170 The Quantitation of 2-Oxo-3-hydroxy Lysergic Acid Diethylamide (O-H-LSD) in Human Urine Specimens, a Metabolite of LSD: Comparative Analysis Using Liquid ChromatographyÐSelected Ion Monitoring Mass Spectrometry and Liquid ChromatographyÐIon Trap Mass Spectrometry
180 The Use of Nuclear Magnetic Resonance Spectroscopy in the Detection of Drug Intoxication
188 Over-the-Counter Æ5 Anabolic Steroids 5-Androsten-3, 17-dione; 5-Androsten-3b,17b-diol; Dehydroepiandrosterone; and 19-Nor-5-androsten-3,17-dione: Excretion Studies in Men
194 Detection of Triazolam and Its Hydroxy Metabolites in Rat Hair by Reversed-Phase Liquid Chromatography with Electrospray Ionization Mass Spectrometry
202 Tabulation of Alcohol Content of Beer and Malt Beverages
211 GCÐMS Identification of Sympathomimetic Amine Drugs in Urine: Rapid Methodology Applicable for Emergency Clinical Toxicology
223 Using Amphetamine Isomer Ratios to Determine the Compliance of Amphetamine Abusers Prescribers Dexedrine
228 The Application of Supercritical Fluid Extraction to Cocaine and Its Metabolites in Blood and Urine

May/June 1999

Page Title
233 Effects of Pyridinium Chlorochromate Adulterant (Urine Luck) on Testing for Drugs of Abuse and a Method for Quantitative Detection of Chromium (VI) in Urine
238 Determination of Enantiomeric Metabolites of l-Deprenyl, d-Methamphetamine, and Racemic Methamphetamine in Urine by Capillary Electrophoresis: Comparison of Deprenyl Use and Methamphetamine Use
245 Solid-Phase Extraction of 11-Nor-Æ9-Tetrahydrocannabinol- 9-Carboxylic Acid from Urine Drug-Testing Specimens with the Cerex PolyCrom-THCª Column
250 The Use of Low-Resolution FT-IR Spectrometry for the Analysis of Alcohols in Breath
257 Simple and Rapid Determination of Amphetamine, Methamphetamine, and Their Methylenedioxy Derivatives in Urine by Automated In-Tube Solid-Phase Microextraction Coupled with Liquid ChromatographyÐElectrospray Ionization Mass Spectrometry
266 A New Spectrophotometric Method for the Toxicological Diagnosis of Cyanide Poisoning
271 Blood Concentrations of Amitriptyline and Its Metabolite in Rats after Acute Oral Administration of Amitriptyline
275 Chemical Derivatization and the Selection of Deuterated Internal Standard for Quantitative DeterminationÑ Methamphetamine Example
281 Development of Analytical Methods for the Detection of Metaraminol in the Horse
289 An Automated and Simultaneous Solid-Phase Extraction of Æ9-Tetrahydrocannabinol and 11-Nor-9-Carboxy-Æ9-Tetrahydrocannabinol from Whole Blood Using the Zymark RapidTraceª with Confirmation and Quantitation by GCÐEI-MS
296 A Sensitive Immunoassay for Flunitrazepam and Metabolites
300 CASE REPORT: Quetiapine (Seroquel¨) Concentrations in Seven Postmortem Cases
305 CASE REPORT: A Fatality Due To Injection of Tiletamine and Zolazepam

July/August 1999

Page Title
309 Remifentanil in the Horse: Idenification and Detection of its Major Urinary Metabolite
316 Determination of Lidocaine in Hair of Drug Fatalities by Headspace Solid-Phase Microextraction
323 An Assay Evaluation of the Methylene Blue Method for the Detection of Anionic Surfactants in Urine
328 Determination of Methyl Mercury in Whole Blood by EthylationÐGCÐCVAFS after Alkaline DigestionÐSolvent Extraction
333 Comparison of Serum and Salivary Cotinine Measurements by a Sensitive High-Performance Liquid ChromatographyÐTandem Mass Spectrometry Method as an Indicator of Exposure to Tobacco Smoke Among Smokers and Nonsmokers
340 Screening Procedure for Detection of Antidepressants of the Selective Serotonin Reuptake Inhibitor Type and their Metabolites in Urine as Part of a Modified Systematic Toxicological Analysis Procedure using Gas ChromatographyÐ Mass Spectrometry
348 Distribution of Aconitum Alkaloids in Body Fluids and Tissues in a Suicidal Case of Aconite Ingestion
354 Discrimination of Dimethylamphetamine and Methamphetamine Use: Simultaneous Determination of Dimethylamphetamine-N-Oxide and Other Metabolites in Urine by High-Performance Liquid ChromatographyÐ Electrospray Ionization Mass Spectrometry
359 Enhanced Selectivity in the Determination of Æ9-Tetrahydrocannabinol and Two Major Metabolites in Serum Using Ion-Trap GCÐMSÐMS
365 Rapid Multimethod for Verification and Determination of Toxic Pesticides in Whole Blood by Means of Capillary GCÐMS
372 Rapid Analysis of Halothane in Biological Samples using Headspace Solid-Phase Microextraction and Gas ChromatographyÐMass SpectrometryÑA Case of a Double Homicide
377 CASE REPORT: Attempted Suicide by Ingestion of Methoxychlor
381 LETTER TO THE EDITOR: Ephedrine Abuse for Doping Purposes as Demonstrated by Hair Analysis
383 LETTER TO THE EDITOR: Elevated GHB in Citrate- Buffered Blood

September 1999

Page Title
385 Determination of 11-Nor-Æ9-Tetrahydrocannabinol- 9-Carboxylic Acid in a Urine-Based Standard Reference Material by Isotope-Dilution Liquid ChromatographyÐMass Spectrometry with Electrospray Ionization
390 A GCÐMS Method for the Detection of Toluene and Ethylbenzene in Volatile Substance Abuse
395 Simultaneous Analysis of Æ9-THC and its Major Metabolites in Urine, Plasma, and Meconium by GCÐMS Using and Immunoaffinity Extraction Procedure
403 Routine Analysis of 101 Polychlorinated Biphenyl Congeners in Human Serum by Parallel Dual-Column Gas Chromatography with Electron Capture Detection
421 Analysis of Biofluids for Gamma-Hydroxybutyrate (GHB) and Gamma-Butyrolactone (GBL) by Headspace GCÐFID and GCÐMS
429 Determination of Azide in Blood and Urine by Gas ChromatographyÐMass Spectrometry
433 Automated Extraction of 11-nor-Æ9-Tetrahydrocannabinol Carboxylic Acid from Urine Samples Using the ASPEC XLª Solid-Phase Extraction System
438 A Rapid, Sensitive Assay for Cocaine and Its Metabolites in Biological Fluids using Solid-Phase Extraction and High- Performance Liquid Chromatography
442 Total Morphine Stability in Urine Specimens Stored under Various Conditions
448 SHORT COMMUNICATION: Buprenorphine to Norbuprenorphine Ratio in Hair
450 SHORT COMMUNICATION: Retrospective Study of Urinalysis for dl-Amphetamine and dl-Methamphetamine Analysis under Current Department of Defense Guidelines
453 LETTER TO THE EDITOR: A Gas ChromatographyÐPositive Ion Chemical Ionization-Mass Spectrometric Method for Determination of Cocaine, Benzoylecgonine, Ecgonine Methyl Ester, and Norcocaine in Plasma: Detection of Norcocaine in Plasma After Oral Administration of Cocaine
456 LETTER TO THE EDITOR: Evaluation of Intectª Test Strips for Detecting Adulteration of Urine Specimens Used For Drugs-of-Abuse Testing

October 1999

Page Title
458 Cocaine and Metabolite Elimination Patterns in Chronic Cocaine Users During Cessation: Plasma and Saliva Analysis
467 Elimination of Cocaine and Metabolites in Plasma, Saliva, and Urine Following Repeated Oral Administration to Human Volunteers
478 Cocaine and its Major Metabolites in Plasma and Urine Samples in an Urban Emergency Medicine Setting
482 Simultaneous GCÐMS Analysis of meta- and para- Hydroxybenzoylecgonine and Norbenzoylecgonine: A Secondary Method to Corroborate Cocaine Ingestion Using Nonhydrolytic Metabolites
489 Quantitation of Cocaine, Benzoylecgonine, Cocaethylene, Methylecgonine, and Norcocaine in Human Hair by Positive Ion Chemical Ionization (PICI) Gas ChromatographyÐTandem Mass Spectrometry
496 The Disposition of Cocaine and Opiate Analytes in Hair and Fingernails Following Cocaine and Codeine Administration
509 Monitoring Opiate Use in Substance Abuse Treatment Patients With Sweat and Urine Drug Testing
522 Detection Times and Analytical Performance of Commercial Urine Opiate Immunoassays Following Heroin Administration
530 Identification of Hydrocodone in Human Urine Following Controlled Codeine Administration
536 The Effects of Collection Methods of Oral Fluid Codeine Concentrations
543 Liquid ChromatographyÐElectrospray Ionization Mass Spectrometry for the Detection of Lysergide and a Major Metabolite, 2-Oxo-3-Hydroxy-LSD, in Urine and Blood
550 Metabolism of Lysergic Acid Diethylamide (LSD) to 2-Oxo-3-Hydroxy LSD in Human Liver Microsomes and Cyropreserved Human Hepatocytes
557 Detection of Cannabis in Oral Fluid (Saliva) and Forehead Wipes (Sweat) from Impaired Drivers
562 Consumption and Quantitation of Æ9-Tetrahydrocannabinol in Commercially Available Hemp Seed Oil Products
567 Loss of THCCOOH from Urine Specimens Stored in Polypropylene and Polyethylene Containers at Different Temperatures
572 Carbon Monoxide Stability in Stored Postmortem Blood Samples
579 The Characterization of Human Urine for Specimen Validity Determination in Workplace Drug Testing: A Review
589 Performance Evaluation of Four On-Site Drug-Testing Devices for Detection of Drugs of Abuse in Urine
595 Assessment of the Ion-Trap Mass Spectrometer for Routine Qualitative and Quantitative Analysis of Drugs of Abuse Extracted from Urine
602 GCÐMS Analysis of Methamphetamine Impurities: Reactivity of (+)- or (Ð)-Chlorophedrine and cis- or trans-1,2-Dimethyl-3-phenylaziridine
606 Differentiation of Clobenzorex Use from Amphetamine Abuse Using the Metabolite 4-Hydroxyclobenzorex
614 Quantitation of Clonazepam and Its Major Metabolite 7-Aminoclonazepam in Hair
621 Simultaneous Detection and Quantitation of Diethylene Glycol, Ethylene Glycol, and the Toxic Alcohols in Serum using Capillary Column Gas Chromatography
627 Duragesic¨ Transdermal Patch: Postmortem Tissue Distribution of Fentanyl in 25 Cases
635 Lamotrigine Distribution in Two Postmortem Cases
638 Loxapine Intoxication: Case Report and Literature Review
642 Fatal Strychnine Poisoning: Application of Gas Chromatography and Tandem Mass Spectrometry
648 An Unusual Multiple Drug Intoxication Case Involving Citalopram
651 Chiral High-Performance Liquid Chromatographic Analysis of Fluoxetine and Norfluoxetine in Rabbit Plasma, Urine, and Vitreous Humor Using an Acetylated b-Cyclodextrin Column
656 TECHNICAL NOTE: The Analysis of Methadone in Nail Clippings from Patients in a Methadone-Maintenance Program
661 TECHNICAL NOTE: Rapid Gas Chromatographic Procedure for the Determination of Topiramate in Serum
664 CASE REPORT: A Fatality Due to Accidental PineSolª Ingestion

November/December 1999

Page Title
670 Determination of Benzo[a]pyrene and Other Polycyclic Aromatic Hydrocarbons (PAHs) at Trace Levels in Human Tissues
678 Determination of Dialkyl Phosphates in Human Urine using Gas ChromatographyÐMass Spectrometry
685 Analysis of Six Anticonvulsant Drugs using Solid-Phase Extraction, Deuterated Internal Standards, and Gas ChromatographyÐMass Spectrometry
691 Determination of (+)- and (Ð)-Bromoisovalerylurea in Sera of Overdosed Subjects
696 Extraction and Cleanup Methods for Analysis of Phenolic and Neutral Organohalogens in Plasma
704 A Highly Sensitive Spectrophotometric Method with Solid-Phase Extraction for the Determination of Methylmercury in Human Hair
708 Investigation of Nitrite Adulteration on the Immunoassay and GCÐMS Analysis of Cannabinoids in Urine Specimens
715 GCÐMS Analysis of the Total Æ9-THC Content of Both Drug- and Fiber-Type Cannabis Seeds
718 Automated In-Tube Solid-Phase Microextraction Coupled with Liquid ChromatographyÐElectrospray Ionization Mass Spectrometry for the Determination of Selected Benzodiazepines
726 New Fluorescence Polarization Immunoassays for Analysis of Barbiturates and Benzodiazepines in Serum and Urine: Performance Characteristics

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