Published: Journal of Analytical Toxicology, Volume 24, Number 1, January/February, pp.22-26
Tetrachloroethylene and Trichloroethylene Fatality: Case Report
and Simple Headspace SPME–Capillary Gas Chromatographic Determination in
Tissues
B. Dehon, L. Humbert,
L. Devisme, M. Stievenart, D. Mathieu, N. Houdret, and M. Lhermitte
Unité Fonctionnelle
de Toxicologie, Laboratoire de Biochimie et de Biologie Moléculaire,
Service d‘Anatomie et Cytologie Pathologiques, and Urgence Respiratoire
et Réanimation Médicale, Hôpital Calmette, rue du Professeur
J. Leclercq, 59037 Lille, France
We describe a simple, precise, and sensitive assay of tetrachloroethylene and trichloroethylene in tissues, suitable both for emergency cases and forensic medicine. The method employs headspace solid phase microextraction–capillary gas chromatography and electron capture detection. The case is relative to a 45-year-old woman discovered unconscious in a laundry area. The concentrations of the solvents in tissues were determined and compared to other previously published fatalities.
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