Published: Journal of Analytical Toxicology, Volume 22, Number 5, September 1998, pp. 345–354.

2C-B: A New Psychoactive Phenylethylamine Recently Discovered in Ecstasy Tablets Sold on the Swiss Black Market
C. Giroud, M. Augsburger, L. Rivier, P. Mangin, F. Sadeghipour, E. Varesio, J.L. Veuthey, and P. Kamalaprija

This study sought to identify, by means of several analytical methods (GC–MS, HPLC–DAD, CE–DAD, FTIR, and NMR), 4-bromo-2,5-dimethoxyphenethylamine (2C-B), which was found in two sets of tablets obtained from the Swiss black market. Unequivocal identification of 2C-B was only achieved by a combination of mass spectrometric and NMR analysis. Quantitation of 2C-B was performed by HPLC–DAD and CE–DAD. The amounts of 2C-B found in the tablets (3–8 mg) were in the range of the minimum quantity required to induce the effects characteristic of this drug.

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