Published: Journal of Analytical Toxicology, Volume 21, Number 3, May/June 1997, pp. 232–235.
CASE REPORT: Concentrations
of Heroin, 06-Monoacetylmorphine, and Morphine in a Lethal Case
Following an Oral Heroin Overdose
P.R. Rop, M.
Fornaris, T. Salmon, J. Burle, and M. Bresson
A case of lethal overdose by heroin ingestion is presented. The concentrations of drugs were measured several hours after death. Heroin, 06-monoacetylmorphine, and morphine were identified and quantitated in blood, urine, and gastrointestinal contents by gas chromatography–mass spectrometry and high-performance liquid chromatography. Concentrations of heroin, 06-monoacetylmorphine, and morphine were 109, 168, and 1140 ng/mL, respectively, in blood and 17, 12, and 425 ng/g, respectively, in gastrointestinal content. In urine, however, only morphine was detected at 3650 ng/mL.
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