Published: Journal of Analytical Toxicology, Volume 21, Number 3, May/June 1997, pp. 228–231.

CASE REPORT: A Fatal Case of Betaxolol Poisoning
F. Berthault, P. Kintz, A. Tracqui, and P. Mangin

We report the first case in the literature of fatal betaxolol (Kerlone®) self-poisoning. After a single-step liquid–liquid alkaline extraction, betaxolol was identified by a high-performance liquid chromatographic–diode array detection screening procedure and then quantitated in cardiac blood, heart, brain, muscle, spleen, stomach contents, duodenum contents, liver, and kidney. The blood betaxolol concentration was 36 mg/L.

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