Published: Journal of Analytical Toxicology, Volume 21, Number 3, May/June 1997, pp. 221–222.

CASE REPORT: A Fatal Case of Amlodipine Poisoning
S.H. Cosbey and D.J.L. Carson

A fatal case attributed to amlodipine intoxication is presented. The deceased was a 15-year-old girl who allegedly ingested 14 10-mg Istin tablets. Amlodipine concentration in peripheral blood was determined (2.7 mg/L) and was compared with published therapeutic and toxic data for amlodipine and some other dihydropyridine calcium channel-blocking agents. Amlodipine concentrations in liver, blood, and stomach contents were also determined.

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